C265
Monoclonal Anti-CaM Kinase IIα (CaMKIIα) antibody produced in mouse
clone 6G9, purified immunoglobulin, buffered aqueous solution
Synonym(s):
Anti-CAMKA, Anti-CaMKIINalpha, Anti-CaMKIIalpha, Anti-MRD53, Anti-MRT63
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About This Item
Conjugate:
unconjugated
Clone:
6G9, monoclonal
Application:
IF, WB
Citations:
20
biological source
mouse
Quality Level
conjugate
unconjugated
antibody form
purified immunoglobulin
antibody product type
primary antibodies
clone
6G9, monoclonal
form
buffered aqueous solution
mol wt
antigen ~50 kDa
species reactivity
rat, mouse
technique(s)
indirect immunofluorescence: suitable using rat hippocampus, western blot: 0.5-1.0 μg/mL
isotype
IgG1
UniProt accession no.
shipped in
dry ice
storage temp.
−20°C
target post-translational modification
unmodified
Gene Information
rat ... Camk2a(25400)
General description
CaM Kinase II α is a Ca2+/calmodulin-dependent kinase that belongs to the serine/threonine protein kinases family. It facilitates the regulation of NMDAR-dependent AMPA receptor trafficking to the synapses. Mouse anti-CaM kinase II α antibody reacts specifically with phosphorylated and non-phosphorylated forms of native and recombinant CaM (Ca2+/calmodulin-dependent) kinase II α subunit in rats. The product has shown no reactivity for phosphorylated or non-phosphorylated β subunit (60kD).
Immunogen
partially purified rat CaM kinase II.
Application
Monoclonal Anti-CaM Kinase IIα (CaMKIIα) antibody produced in mouse has been used in immunohistochemistry and western blotting.
Physical form
Solution in phosphate buffered saline containing 0.05% sodium azide
Disclaimer
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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Storage Class
10 - Combustible liquids
wgk
nwg
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, multi-purpose combination respirator cartridge (US)
Regulatory Information
常规特殊物品
低风险生物材料
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Joana S Ferreira et al.
The Journal of neuroscience : the official journal of the Society for Neuroscience, 35(22), 8462-8479 (2015-06-05)
NMDA receptors play a central role in shaping the strength of synaptic connections throughout development and in mediating synaptic plasticity mechanisms that underlie some forms of learning and memory formation in the CNS. In the hippocampus and the neocortex, GluN1
Esther Del Cid-Pellitero et al.
Frontiers in systems neuroscience, 11, 17-17 (2017-04-15)
Neuronal activity is regulated in a homeostatic manner through changes in inhibitory GABA and excitatory glutamate (Glu) AMPA (A) receptors (GluARs). Using immunofluorescent staining, we examined whether calcium/calmodulin-dependent protein kinase IIα (CaMKIIα)-labeled (+) excitatory neurons in the barrel cortex undergo
Roshni Ramachandran et al.
Cephalalgia : an international journal of headache, 38(6), 1057-1070 (2017-07-26)
Background A common characteristic of migraine-inducing substances is that they cause headache and no pain in other areas of the body. Few studies have compared pain mechanisms in the trigeminal and spinal systems and, so far, no major differences have
Global Trade Item Number
| SKU | GTIN |
|---|---|
| C265-100UL | 04061837913433 |