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Merck
CN

C3630

Creatine monohydrate

≥98%, suitable for cell culture

Synonym(s):

Creatine hydrate, Creatine, monohydrate, N-(aminoiminomethyl)-N-methyl-glycine hydrate

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About This Item

Empirical Formula (Hill Notation):
C4H9N3O2 · H2O
CAS Number:
Molecular Weight:
149.15
NACRES:
NA.26
PubChem Substance ID:
UNSPSC Code:
12352209
EC Number:
200-306-6
MDL number:
Beilstein/REAXYS Number:
7942755
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Product Name

Creatine monohydrate, ≥98%

Quality Level

assay

≥98%

form

powder

technique(s)

cell culture | mammalian: suitable

color

white to off-white

mp

292 °C

SMILES string

O.CN(CC(O)=O)C(N)=N

InChI

1S/C4H9N3O2.H2O/c1-7(4(5)6)2-3(8)9;/h2H2,1H3,(H3,5,6)(H,8,9);1H2

InChI key

MEJYXFHCRXAUIL-UHFFFAOYSA-N

Application

Creatine (Cr) and phosphocreatine (PCr) are involved with rapid ATP production primarily in skeletal muscle tissue via the action of creatine kinase(s). Creatine may be used as a supplement to study its uptake mechanism and metabolism of action.

Biochem/physiol Actions

Creatine is a nitrogenous compound that acts as a high-energy reservoir for the rapid regeneration of ATP.
Creatine is a nitrogenous compound that acts as a high-energy reservoir for the rapid regeneration of ATP. Approximately 95% of creatine is found in skeletal muscle, primarily as phosphocreatine. Creatine can be acquired through dietary consumption or formed from L-arginine, glycine, and L-methionine in a multi-step reaction that occurs in the kidneys and liver. Creatine is then transported to muscle tissue. Creatine supplementation is used for the enhancement of sports performance, primarily by increasing muscle mass. Creatine is also being investigated as a treatment of neuromuscular diseases, where it may aid in neuroprotection and by improving the cellular bioenergetic state.


Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

dust mask type N95 (US), Eyeshields, Gloves



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Andrina Stäubli et al.
Human molecular genetics, 26(21), 4203-4214 (2017-11-01)
Membrane transporters influence biological functions in the ocular lens. Here, we investigate the monocarboxylate transporter 12 (MCT12), also called creatine transporter 2 (CRT2), which is found in the ocular lens and is involved in cataract. As the age-related form affects
Caro-Lyne DesRoches et al.
Gene, 565(2), 187-191 (2015-04-12)
Creatine transporter deficiency (CRTR-D) is an X-linked inherited disorder of creatine transport. All males and about 50% of females have intellectual disability or cognitive dysfunction. Creatine deficiency on brain proton magnetic resonance spectroscopy and elevated urinary creatine to creatinine ratio
Jeffrey S Martin et al.
Journal of the International Society of Sports Nutrition, 14, 38-38 (2017-09-30)
We sought to determine if a pre-workout supplement (PWS), containing multiple ingredients thought to enhance blood flow, increases hyperemia associated with resistance training compared to placebo (PBO). Given the potential interaction with training loads/time-under-tension, we evaluated the hyperemic response at



Global Trade Item Number

SKUGTIN
C3630-100G04061833486061
C3630-1KG04061833486078