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Merck
CN

C3633

Cystathionine

≥90% (HPLC)

Synonym(s):

DL,DL-allo-Cystathionine, S-(2-Amino-2-carboxyethyl)homocysteine

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About This Item

Linear Formula:
HOOCCH(NH2)CH2CH2SCH2CH(NH2)COOH
CAS Number:
Molecular Weight:
222.26
NACRES:
NA.26
PubChem Substance ID:
UNSPSC Code:
12352209
EC Number:
208-613-7
MDL number:
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Product Name

Cystathionine, ≥90% (HPLC)

Quality Level

assay

≥90% (HPLC)

form

powder

color

white to off-white

mp

281 °C (dec.)

storage temp.

2-8°C

SMILES string

NC(CCSCC(N)C(O)=O)C(O)=O

InChI

1S/C7H14N2O4S/c8-4(6(10)11)1-2-14-3-5(9)7(12)13/h4-5H,1-3,8-9H2,(H,10,11)(H,12,13)

InChI key

ILRYLPWNYFXEMH-UHFFFAOYSA-N

Gene Information

human ... BHMT(635)

Biochem/physiol Actions

Cystathionine is an intermediate in the biosynthesis of the amino acid cysteine. Cystathionine is used as a substrate to differentiate and analyze cystathionine gamma-lyase(s).

Preparation Note

Prepared by method of Stekol.

Other Notes

A mixture of 4 stereoisomers; L-, D-, L-allo- and D-allo-cystathionine.


Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)



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A new synthesis of S-(beta-amino-beta-carboxyethyl) homocysteine (cystathionine) and S-bis(gamma-amino-gamma -carboxypropyl) sulfide (homolanthionine).
J A STEKOL
The Journal of biological chemistry, 173(1), 153-157 (1948-03-01)
Hydrogen Sulfide Inhibits Cigarette Smoke-Induced Endoplasmic Reticulum Stress and Apoptosis in Bronchial Epithelial Cells.
Fan Lin et al.
Frontiers in pharmacology, 8, 675-675 (2017-10-17)
Zhi-Jun Wang et al.
Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology, 42(3), 859-875 (2017-06-24)
Hydrogen sulfide (H2S) is now admitted as a third gasotransmitter together with nitric oxide (NO) and carbon monoxide (CO), albeit it was originally considered as a foul and poisonous gas. Endogenous H2S production in mammalian cells is counting on the



Global Trade Item Number

SKUGTIN
C3633-100MG04061833486085
C3633-500MG04061832722009