C5135
Castor Oil, Ethoxylated
pH range 6.0-8.0
Synonym(s):
Cremophor® EL, EL, Macrogolglycerol ricinoleate, PEG-35 castor oil, Polyoxyl-35 castor oil
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About This Item
description
non-ionic
Quality Level
form
liquid
mol wt
~2500 g/mol
pH range
6.0-8.0
HLB
12 - 14
application(s)
sample preservation
SMILES string
ClCC(OC(=O)N)CCl
InChI
1S/C4H7Cl2NO2/c5-1-3(2-6)9-4(7)8/h3H,1-2H2,(H2,7,8)
InChI key
JMNCUXPHXKHBPY-UHFFFAOYSA-N
General description
Castor Oil, Ethoxylated is polyethylene oxide surfactant and is viscous in nature. It has a hydrophobic-lipophilic balance value in the range of 12-14.
Castor Oil, Ethoxylated is a nonionic solubilizer and emulsifier made by reacting castor oil with ethylene oxide. It is a pale yellow oily liquid that is clear at temperatures above 26°C. It has a faint but characteristic odour.
Application
Castor Oil, Ethoxylated has been used as a detergent to improve the solubility of dye and to increase the transmembrane permeation. It has been used as a vehicle for drug/stimulant delivery in cells.
Biochem/physiol Actions
Castor Oil, Ethoxylated is used in lipid-based formulations for drugs and solubilization of cosmetics. Castor Oil, Ethoxylated is suitable for the production of semi-solid and liquid formulations of water-insoluble actives and other hydrophobic compounds. Due to its emulsification functionality, it finds application in biological membrane- based drug transport studies.
Other Notes
A derivative of castor oil and ethylene oxide.
Legal Information
Cremophor is a registered trademark of BASF SE
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Storage Class
10 - Combustible liquids
flash_point_f
494.6 °F - Not applicable
flash_point_c
257 °C - Not applicable
ppe
Eyeshields, Gloves
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A nonionic polyethylene oxide (PEO) surfactant model: experimental and molecular dynamics studies of Kolliphor EL
Suys EJA, et al.
Journal of Pharmaceutical Sciences, 108(1), 193-204 (2019)
Global Trade Item Number
| SKU | GTIN |
|---|---|
| C5135-1KG | 04061833501788 |
| C5135-500G | 04061833501795 |