C8755
L-Cystine
≥98% (TLC)
Synonym(s):
(R,R)-3,3′-Dithiobis(2-aminopropionic acid)
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About This Item
Linear Formula:
[-SCH2CH(NH2)CO2H]2
CAS Number:
Molecular Weight:
240.30
NACRES:
NA.26
PubChem Substance ID:
eCl@ss:
32160406
UNSPSC Code:
12352209
EC Number:
200-296-3
MDL number:
Beilstein/REAXYS Number:
1728094
Product Name
L-Cystine, ≥98% (TLC), crystalline
Quality Level
assay
≥98% (TLC)
form
crystalline
color
white to off-white
mp
>240 °C (dec.) (lit.)
solubility
1 M HCl: 50 mg/mL, clear, colorless to faintly yellow
application(s)
cell analysis
peptide synthesis
storage temp.
room temp
SMILES string
N[C@@H](CSSC[C@H](N)C(O)=O)C(O)=O
InChI
1S/C6H12N2O4S2/c7-3(5(9)10)1-13-14-2-4(8)6(11)12/h3-4H,1-2,7-8H2,(H,9,10)(H,11,12)/t3-,4-/m0/s1
InChI key
LEVWYRKDKASIDU-IMJSIDKUSA-N
Application
L-Cystine has been used in in vitro cystine solubility assay to identify potential drugs that influence cystine solubility. It is also used as a supplement of phosphate-buffered saline to slice and wash periprosthetic tissues.
Biochem/physiol Actions
Cysteine is the source of disulfide linkages in proteins and has a role in sulfur transport. It undergoes rapid oxidation to form cystine at physiological pH. L-cystine is crucial for oxygen production and low density lipoprotein modification by arterial smooth muscle cells. It also has a role in the synthesis of glutathione.
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Storage Class
11 - Combustible Solids
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type N95 (US)
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The x(c)- cystine/glutamate antiporter: a potential target for therapy of cancer and other diseases
Maisie Lo
Journal of Cellular Physiology, 215(215) (2008)
Mass Spectrometry-based in vitro Assay to Identify Drugs that Influence Cystine Solubility
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Bio-protocol, 7(14), e2417-e2417 (2017)
Global Trade Item Number
| SKU | GTIN |
|---|---|
| C8755-100G | 04061838581303 |
| C8755-1KG | 04061833522738 |
| C8755-500G | 04061833522745 |