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CNSBR007

Oligomycin A

Name: Oligomycin A
Brand: SIGMA

≥95% (HPLC), powder

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About This Item

Empirical Formula (Hill Notation):

C₄₅H₇₄O₁₁

CAS Number:

579-13-5

Molecular Weight:

791.06

UNSPSC Code:

51101500

Beilstein/REAXYS Number:

5702132

MDL number:

MFCD00065705

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Properties

Quality Level

200

assay

≥95% (HPLC)

form

powder

color

white to off-white

antibiotic activity spectrum

fungi

mode of action

enzyme | inhibits

storage temp.

−20°C

SMILES string

CCC1CCC2OC3(CC[C@@H](C)C(C[C@H](C)O)O3)[C@H](C)C(OC(=O)\C=C\[C@@H](C)[C@H](O)[C@@H](C)C(=O)[C@H](C)[C@@H](O)[C@H](C)C(=O)[C@@](C)(O)[C@H](O)[C@@H](C)C\C=C\C=C\1)[C@H]2C

InChI

1S/C45H74O11/c1-12-34-17-15-13-14-16-27(4)42(51)44(11,53)43(52)32(9)40(50)31(8)39(49)30(7)38(48)26(3)18-21-37(47)54-41-29(6)35(20-19-34)55-45(33(41)10)23-22-25(2)36(56-45)24-28(5)46/h13-15,17-18,21,25-36,38,40-42,46,48,50-51,53H,12,16,19-20,22-24H2,1-11H3/b14-13+,17-15+,21-18+/t25-,26-,27+,28+,29+,30-,31+,32+,33-,34?,35?,36?,38+,40-,41?,42-,44+,45?/m1/s1

InChI key

MNULEGDCPYONBU-VVXVDZGXSA-N

Description

General description

Chemical structure: macrolide

Application

Oligomycin was used to inhibit sucrose synthesis and ¹⁴C translocation in sunflower leaves, to study antibiotic resistance, and to study carotid chemoreceptor responses to O₂ and CO₂ in the cat. Inhibits the growth of Rhodotorula glutinis, Aspergillus niger and other molds.

Biochem/physiol Actions

Oligomycin blocks oxidative phosphorylation and the electron transport chain by inhibiting membrane bound mitochondrial ATP synthase (ATPase) and proton channel (pump, FO subunit) blocker.

Features and Benefits

High quality antibiotic suitable for mulitple research applications.

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Storage Class

11 - Combustible Solids

flash_point_f

Not applicable

flash_point_c

Not applicable

Regulatory Information

涉药品监管产品

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Global Trade Item Number

SKU	GTIN
CNSBR007-5MG	04065272682022