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Merck
CN

D4540

Dimethyl sulfoxide

≥99.5% (GC), suitable for plant cell culture

Synonym(s):

DMSO

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About This Item

Linear Formula:
(CH3)2SO
CAS Number:
Molecular Weight:
78.13
UNSPSC Code:
12191502
NACRES:
NA.71
PubChem Substance ID:
EC Number:
200-664-3
Beilstein/REAXYS Number:
506008
MDL number:
Assay:
≥99.5% (GC)
Technique(s):
cell culture | plant: suitable, cryopreservation: suitable
Bp:
189 °C (lit.)
Vapor pressure:
0.42 mmHg ( 20 °C)
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vapor density

2.7 (vs air)

vapor pressure

0.42 mmHg ( 20 °C)

assay

≥99.5% (GC)

form

liquid

autoignition temp.

573 °F

expl. lim.

42 %, 63 °F

technique(s)

cell culture | plant: suitable, cryopreservation: suitable

impurities

<0.1% water (Karl Fischer)

color

colorless

refractive index

n20/D 1.479 (lit.)

bp

189 °C (lit.)

mp

16-19 °C (lit.)

solubility

H2O: miscible (completely)

density

1.10 g/mL (lit.)

SMILES string

CS(C)=O

InChI

1S/C2H6OS/c1-4(2)3/h1-2H3

InChI key

IAZDPXIOMUYVGZ-UHFFFAOYSA-N

Application

Dimethyl sulfoxide has been used:
  • in the preparation of bisphenol A (BPA)
  • in cell proliferation assay (MTT assay)
  • in chemosensitivity assay
  • as the vehicle control in all experiments like apoptosis assay
  • in ethoxyresorufin-O-deethylation (EROD) assay

Biochem/physiol Actions

DMSO (dimethyl sulfoxide), an organic solvent possesses several pharmaceutical activities such as analgesic, diuretic, bacteriostatic, membrane-penetrant, anti-inflammatory, vasodilatory and cholinesterase inhibitory effects. It is a by-product of the lumber industry and used as an industrial solvent. DMSO also serves as a therapeutic agent to treat interstitial cystitis and arthritis.

Disclaimer

Supercools easily and remelts slowly at room temperature. Solidified product can be re-liquified by warming to room temperature without detriment to the product.


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Storage Class

10 - Combustible liquids

wgk

WGK 1

flash_point_f

188.6 °F - closed cup

flash_point_c

87 °C - closed cup

ppe

Eyeshields, Gloves, type ABEK (EN14387) respirator filter



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Articles

用于细胞系冷冻保存的良好细胞库操作实践概述。

Overview of good cell banking practices for cell line cryopreservation purposes.


Evaluation of the sub-lethal toxicity of Cu, Pb, bisphenol A and polychlorinated biphenyl to the marine dinoflagellate Cochlodinium polykrikoides
Ebenezer V and Ki J S
Algae, 27(1), 63-63 (2012)
Pharmacotherapy of joint and tendon disease
Equine Sports Medicine and Surgery E-Book: Basic and clinical sciences of the equine athlete, 473-473 (2013)
Herbal and nutritional supplements for painful conditions
Pain Procedures in Clinical Practice, 187-204 (2011)



Global Trade Item Number

SKUGTIN
D4540-1L04061838259295
D4540-100ML04061838259288
D4540-500ML04061838259301