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D5038

2′-Deoxyguanosine 5′-triphosphate trisodium salt solution

100 mM (pH 7)

Synonym(s):

dGTP-Na3

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About This Item

Empirical Formula (Hill Notation):
C10H13N5Na3O13P3
CAS Number:
Molecular Weight:
573.13
NACRES:
NA.52
PubChem Substance ID:
UNSPSC Code:
41106305
EC Number:
300-026-5
MDL number:
Assay:
≥99%
Form:
liquid
Storage temp.:
−20°C
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assay

≥99%

Quality Level

form

liquid

concentration

100 mM (pH 7)

color

colorless

foreign activity

DNase, RNase, none detected

shipped in

dry ice

storage temp.

−20°C

SMILES string

[Na+].[Na+].[Na+].NC1=Nc2c(ncn2[C@H]3C[C@H](O)[C@@H](COP([O-])(=O)OP([O-])(=O)OP(O)([O-])=O)O3)C(=O)N1

InChI

1S/C10H16N5O13P3.3Na/c11-10-13-8-7(9(17)14-10)12-3-15(8)6-1-4(16)5(26-6)2-25-30(21,22)28-31(23,24)27-29(18,19)20;;;/h3-6,16H,1-2H2,(H,21,22)(H,23,24)(H2,18,19,20)(H3,11,13,14,17);;;/q;3*+1/p-3/t4-,5+,6+;;;/m0.../s1

InChI key

IWGGLKOTEOCWQP-BIHLCPNHSA-K

General description

2′-Deoxyguanosine 5′-triphosphate (dGTP) is made of a guanine nucleobase attached to deoxyribose and a 5′-hydroxyl on the sugar linked to a chain of three phosphate residues. It is used by the cells for the synthesis of DNA with the help of DNA polymerase.

Application

2′-Deoxyguanosine 5′-triphosphate trisodium salt solution has been used:

  • in a reverse transcription-polymerase chain reaction (RT-PCR) for DNA amplification.
  • as a component of the PCR mix for in situ reverse transcription-polymerase chain reaction (RT-PCR) amplification of mRNA from prokaryotic and eukaryotic ribosomes
  • to study the mutations in the HBB gene via amplification refractory mutation system (ARMS)-PCR
2′-Deoxyguanosine 5′-triphosphate trisodium salt is utilized for methods such as DNA sequencing, PCR and other DNA polymerase based DNA synthesis and repair techniques.


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Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)



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Functional Protein Microarrays in Drug Discovery (2008)



Global Trade Item Number

SKUGTIN
D5038-.1MMO04061833451038
D5038-25UMO04061833697030