D6277
N-Decanoyl-N-methylglucamine
≥98% (GC)
Synonym(s):
N-(D-Glucityl)-N-methyldecanamide, N-Decanoyl-N-methyl-D-glucamine, MEGA-10
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About This Item
Empirical Formula (Hill Notation):
C17H35NO6
CAS Number:
Molecular Weight:
349.46
UNSPSC Code:
12161900
NACRES:
NA.25
PubChem Substance ID:
MDL number:
Beilstein/REAXYS Number:
6974359
description
non-ionic
Quality Level
assay
≥98% (GC)
form
powder
mol wt
349.46 g/mol
technique(s)
ligand binding assay: suitable, protein purification: suitable
CMC
6-7 mM (20-25°C)
storage temp.
2-8°C
SMILES string
OCC(O)C(O)C(O)C(O)CN(C)C(CCCCCCCCC)=O
InChI
1S/C17H35NO6/c1-3-4-5-6-7-8-9-10-15(22)18(2)11-13(20)16(23)17(24)14(21)12-19/h13-14,16-17,19-21,23-24H,3-12H2,1-2H3
InChI key
UMWKZHPREXJQGR-UHFFFAOYSA-N
General description
N-Decanoyl-N-methylglucamine is a nonionic detergent used in lysis buffers.
Application
N-Decanoyl-N-methylglucamine has been used in a study to assess the effect of surfactants on wetting behavior of super-hydrophobic surfaces. It has also been used in a study to investigate the clinical impact of Human metapneumovirus (hMPV) vaccines on Syrian golden hamsters.
Non-ionic, dialyzable detergent used for the solubilization of membrane proteins
Storage Class
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type N95 (US)
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Optimal concentrations of N-decanoyl-N-methylglucamine and sodium dodecyl sulfate allow the extraction and analysis of membrane proteins
Chuang, J., et al.
Analytical Biochemistry, 418, 3-3 (2011)
Khemraj Budachetri et al.
mBio, 11(4) (2020-07-30)
Ehrlichia chaffeensis is an obligatory intracellular bacterium that causes human monocytic ehrlichiosis, an emerging disease transmitted by the Lone Star tick, Amblyomma americanum. E. chaffeensis outer membrane protein entry triggering protein of Ehrlichia (EtpE) is necessary for bacterial entry into
R C Poole et al.
The Biochemical journal, 283 ( Pt 3), 855-862 (1992-05-01)
1. Intact erythrocytes were incubated with 100 microM-4,4'-di-isothiocyanostilbene-2,2'-disulphonate (DIDS), a concentration sufficient to inhibit lactate transport irreversibly by 65%. DIDS-labelled proteins were detected by immunoblotting of erythrocyte membrane proteins with an anti-DIDS antibody. Labelled polypeptides of 35-45 kDa in rat
Global Trade Item Number
| SKU | GTIN |
|---|---|
| D6277-5G | 04061832888491 |
| D6277-1G | 04061833587461 |