Skip to Content
Merck
CN

Key Documents

View All Documentation

D7000

Deoxycorticosterone acetate

synthetic (organic), ≥98% (HPLC), mineralocorticoid and glucocorticoid, powder

Synonym(s):

11-Deoxycorticosterone acetate, 21-Acetoxy-4-pregnene-3,20-dione, 21-Acetoxyprogesterone, 21-Hydroxy-4-pregnene-3,20-dione 21-acetate, 21-Hydroxyprogesterone 21-acetate, 4-Pregnen-21-ol-3,20-dione 21-acetate, Cortexone acetate, DOC acetate

Sign In to View Organizational & Contract Pricing.

Select a Size

Change View

About This Item

Empirical Formula (Hill Notation):
C23H32O4
CAS Number:
56-47-3
Molecular Weight:
372.50
NACRES:
NA.77
PubChem Substance ID:
24894065
UNSPSC Code:
12352200
EC Number:
200-275-9
MDL number:
MFCD00003660
Beilstein/REAXYS Number:
2570798
Assay:
≥98% (HPLC)
Form:
powder
Quality level:
200
Technical Service
Need help? Our team of experienced scientists is here for you.
Let Us Assist

Product Name

Deoxycorticosterone acetate,

biological source

synthetic (organic)

Quality Level

200

sterility

non-sterile

assay

≥98% (HPLC)

form

powder

solubility

H2O: insoluble, acetone: soluble (1 in 30), alcohol: soluble (1 in 50), chloroform: freely soluble, dioxane: slightly soluble, vegetable oils: slightly soluble

shipped in

ambient

storage temp.

room temp

SMILES string

[H][C@@]12CCC3=CC(=O)CC[C@]3(C)[C@@]1([H])CC[C@]4(C)[C@]([H])(CC[C@@]24[H])C(=O)COC(C)=O

InChI

1S/C23H32O4/c1-14(24)27-13-21(26)20-7-6-18-17-5-4-15-12-16(25)8-10-22(15,2)19(17)9-11-23(18,20)3/h12,17-20H,4-11,13H2,1-3H3/t17-,18-,19-,20+,22-,23-/m0/s1

InChI key

VPGRYOFKCNULNK-ACXQXYJUSA-N

Gene Information

human ... NR3C2(4306)

General description

Deoxycorticosterone acetate is an endogenous neurosteroid found in brain and peripheral circulation, which is produced by progesterone. It is both a mineralocorticoid and a glucocorticoid. It is used to treat adrenocortical insufficiency or Addison′s disease. Deoxycorticosterone acetate improves insulin sensitivity. It acts as a precursor to glucocorticoid corticosterone and the GABAergic neuroactive steroid (3α,5α)-3,21-dihydroxypregnan-20-one.

Application

Deoxycorticosterone acetate has been used to induce hypertensive pregnancy. It has also been used to investigate the effect of low epicatechin dosing on the cardiovascular function of deoxycorticosterone acetate (DOCA)-salt hypertensive rats.

Still not finding the right product?

Explore all of our products under Deoxycorticosterone acetate

Storage Class

11 - Combustible Solids

wgk

WGK 3

ppe

Eyeshields, Gloves, type N95 (US)

Regulatory Information

涉药品监管产品

This item has

Choose from one of the most recent versions:

Certificates of Analysis (COA)

Lot/Batch Number
SLBZ1138
SLBW1334
SLBW0182
SLBV5396
082K1761

Don't see the Right Version?

If you require a particular version, you can look up a specific certificate by the Lot or Batch number.

Search for a COA

Already Own This Product?

Find documentation for the products that you have recently purchased in the Document Library.

Visit the Document Library

Genetic analysis of the neurosteroid deoxycorticosterone and its relation to alcohol phenotypes: identification of QTLs and downstream gene regulation
Porcu P, et al.
PLoS ONE, 6(4), e18405-e18405 (2011)
C Kobbe et al.
Journal of dentistry, 91, 103243-103243 (2019-11-16)
Assessment of the influence of colour changes during the re-wetting process as a possible predictor for the final result after resin infiltration to mask post-orthodontic white spot lesions. Resin infiltration (ICON; DMG, Hamburg, Germany) was performed according to the manufacturer's
(-)-Epicatechin Reduces Blood Pressure and Improves Left Ventricular Function and Compliance in Deoxycorticosterone Acetate-Salt Hypertensive Rats
Jackson D, et al.
Molecules (Basel), 23(7), 1511-1511 (2018)
View All Related Papers

Global Trade Item Number

SKUGTIN
D7000-5G04061835512447
D7000-1G04061833588055
D7000-25G04061833588062