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E1149

Estriol

Name: Estriol
Brand: SIGMA

meets USP testing specifications

Synonym(s):

1,3,5(10)-Estratriene-3,16α,17β-triol, 16α-Hydroxyestradiol, 3,16α,17β-Trihydroxy-1,3,5(10)-estratriene

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About This Item

Empirical Formula (Hill Notation):

C₁₈H₂₄O₃

CAS Number:

50-27-1

Molecular Weight:

288.38

UNSPSC Code:

12352212

NACRES:

NA.21

PubChem Substance ID:

24894391

EC Number:

200-022-2

Beilstein/REAXYS Number:

2508172

MDL number:

MFCD00003691

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Properties

agency

USP/NF, meets USP testing specifications

mp

280-282 °C (lit.)

SMILES string

C[C@]12CC[C@H]3[C@@H](CCc4cc(O)ccc34)[C@@H]1C[C@@H](O)[C@@H]2O

InChI

1S/C18H24O3/c1-18-7-6-13-12-5-3-11(19)8-10(12)2-4-14(13)15(18)9-16(20)17(18)21/h3,5,8,13-17,19-21H,2,4,6-7,9H2,1H3/t13-,14-,15+,16-,17+,18+/m1/s1

InChI key

PROQIPRRNZUXQM-ZXXIGWHRSA-N

Gene Information

human ... SERPINA6(866)
mouse ... Esr1(13982)
rat ... Ar(24208)

Description

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pictograms

GHS08

signalword

Danger

hcodes

H351,H360FD,H362

Hazard Classifications

Carc. 2 - Lact. - Repr. 1A

Storage Class

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

ppe

Eyeshields, Gloves, type P3 (EN 143) respirator cartridges

pcodes

P202 - P260 - P263 - P264 - P280 - P308 + P313

Regulatory Information

涉药品监管产品

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Fate of estrogenic hormones in wastewater and sludge treatment: A review of properties and analytical detection techniques in sludge matrix.

Hanna Hamid et al.

Water research, 46(18), 5813-5833 (2012-09-04)

Estrogenic hormones (estrone (E1), 17β-estradiol (E2), estriol (E3), 17α-ethinylestradiol (EE2)) are the major contributor to the total estrogenicity in waterways. Presence of these compounds in biosolids is also causing concern in terms of their use as soil amendment. In comparison

The early history of estriol.

E Diczfalusy

Journal of steroid biochemistry, 20(4B), 945-953 (1984-04-01)

The early history of estriol is reviewed with special emphasis on its isolation, identification, quantitation in tissues and body fluids and its unique biogenesis in the human feto-placental unit. The relationship to epimeric estriols and acidic estrogens and the pharmacokinetic

Review of the endometrial safety during intravaginal treatment with estriol.

G P Vooijs et al.

European journal of obstetrics, gynecology, and reproductive biology, 62(1), 101-106 (1995-09-01)

To gain more insight into whether intravaginal treatment of local urogenital complaints with the mild-acting oestrogen estriol is capable of inducing proliferation of the endometrium, the results of the clinical studies that have been published over the years have been

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Global Trade Item Number

SKU	GTIN
E1149-1G	04061826754344