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Merck
CN

E6267

Earle′s Balanced Salts

With sodium bicarbonate, without calcium chloride and magnesium sulfate, liquid, sterile-filtered, suitable for cell culture

Synonym(s):

EBSS

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About This Item

UNSPSC Code:
12352207
NACRES:
NA.75
MDL number:
Technical Service
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Quality Level

sterility

sterile-filtered

form

liquid

technique(s)

cell culture | mammalian: suitable

impurities

endotoxin, tested

components

NaHCO3: 2.2 g/L
phenol red: 0.011 g/L
glucose: 1.0 g/L (Dextro)

shipped in

ambient

storage temp.

room temp

General description

Earle′s Balanced Salts is a balanced salt solution. It is used as an alternative for conventional simulated body fluids (c-SBF).
Recommended for suspension cultures or whenever cell clumping is a problem.

Application

Earle′s Balanced Salts has been used:
  • to induce autophagy in mouse embryonic fibroblasts
  • in the preparation of melanotroph isolation medium
  • in the preparation of DNAse stock solution

Biochem/physiol Actions

Balanced Salt solution participates in providing cells with water, bulk inorganic ions, and nutrients like carbohydrates essential for normal cell metabolism. It acts as an irrigating, transporting, and diluting fluid to maintain cellular osmotic balance. Balance salt solution helps in maintaining the medium within the physiological pH range (7.2 to 7.6).


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Storage Class

12 - Non Combustible Liquids

wgk

WGK 1

flash_point_f

Not applicable

flash_point_c

Not applicable



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Jinyu Wang et al.
The journals of gerontology. Series A, Biological sciences and medical sciences, 73(7), 882-892 (2018-01-19)
Using age of female sexual maturation as a biomarker, we previously identified nuclear receptor interacting protein 1 (Nrip1) as a candidate gene that may regulate aging and longevity. In the current report, we found that the deletion of Nrip1 can
J Bradley Zuchero
Cold Spring Harbor protocols, 2014(8), 826-838 (2014-08-03)
Dorsal root ganglion neurons (DRGs) are sensory neurons that facilitate somatosensation and have been used to study neurite outgrowth, regeneration, and degeneration and PNS and CNS myelination. Studies of DRGs have relied on cell isolation strategies that generally involve extended
Marisa Granato et al.
Autophagy, 11(11), 1978-1986 (2015-09-24)
This study confirms that autophagy is activated concomitantly with KSHV lytic cycle induction, and that autophagy inhibition by BECN1 knockdown reduces viral lytic gene expression. In addition, we extend previous observations and show that autophagy is blocked at late steps



Global Trade Item Number

SKUGTIN
E6267-6X500ML04061833604472
E6267-500ML04061833604465
E6267-500MLSTAB04065272810791