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Merck
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EMU012341

MISSION® esiRNA

targeting mouse Mre11a

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About This Item

NACRES:
NA.51
UNSPSC Code:
41105324
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description

Powered by Eupheria Biotech

Quality Level

product line

MISSION®

form

lyophilized powder

esiRNA cDNA target sequence

CACAGGGAACAAAAGGGAAAAACAGGAGAAGAGATCAACTTTGGGATGCTCATCACAAAACCTGCTTCAGAAGGAGCAACGCTTAGAGTAGAAGACCTCGTAAAGCAGTATTTCCAAACTGCAGAGAAGAATGTTCAGCTCTCGCTGCTGACAGAAAGAGGGATGGGCGAAGCAGTTCAAGAGTTTGTGGACAAGGAAGAGAAAGATGCCATCGAGGAATTAGTGAAGTACCAGCTGGAGAAAACACAGCGGTTTCTTAAGGAGCGCCATATTGATGCTCTGGAAGACAAGATTGATGAGGAGGTCCGACGTTTCCGAGAAAGCAGACAGAGAAATACCAACGAAGAAGATGATGAAGTTCGAGAGGCCATGAGCAGAGCCCGGGCCCTCAGATCACAGTCAGAGACCTCCACCTCAGCCTTT

Ensembl | mouse accession no.

NCBI accession no.

shipped in

ambient

storage temp.

−20°C

Gene Information

General description

MISSION® esiRNA are endoribonuclease prepared siRNA. They are a heterogeneous mixture of siRNA that all target the same mRNA sequence. These multiple silencing triggers lead to highly-specific and effective gene silencing.

For additional details as well as to view all available esiRNA options, please visit SigmaAldrich.com/esiRNA.

Legal Information

MISSION is a registered trademark of Merck KGaA, Darmstadt, Germany


Storage Class

10 - Combustible liquids

flash_point_f

Not applicable

flash_point_c

Not applicable

Regulatory Information

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A Bakr et al.
Nucleic acids research, 43(6), 3154-3166 (2015-03-11)
Ataxia-telangiectasia mutated (ATM) is needed for the initiation of the double-strand break (DSB) repair by homologous recombination (HR). ATM triggers DSB end resection by stimulating the nucleolytic activity of CtIP and MRE11 to generate 3'-ssDNA overhangs, followed by RPA loading



Global Trade Item Number

SKUGTIN
EMU012341-20UG04061828472765
EMU012341-50UG04061828247479