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About This Item
NACRES:
NA.51
UNSPSC Code:
41105324
description
Powered by Eupheria Biotech
Quality Level
product line
MISSION®
form
lyophilized powder
esiRNA cDNA target sequence
CACAGGGAACAAAAGGGAAAAACAGGAGAAGAGATCAACTTTGGGATGCTCATCACAAAACCTGCTTCAGAAGGAGCAACGCTTAGAGTAGAAGACCTCGTAAAGCAGTATTTCCAAACTGCAGAGAAGAATGTTCAGCTCTCGCTGCTGACAGAAAGAGGGATGGGCGAAGCAGTTCAAGAGTTTGTGGACAAGGAAGAGAAAGATGCCATCGAGGAATTAGTGAAGTACCAGCTGGAGAAAACACAGCGGTTTCTTAAGGAGCGCCATATTGATGCTCTGGAAGACAAGATTGATGAGGAGGTCCGACGTTTCCGAGAAAGCAGACAGAGAAATACCAACGAAGAAGATGATGAAGTTCGAGAGGCCATGAGCAGAGCCCGGGCCCTCAGATCACAGTCAGAGACCTCCACCTCAGCCTTT
Ensembl | mouse accession no.
NCBI accession no.
shipped in
ambient
storage temp.
−20°C
Gene Information
mouse ... MRE11A(17535), Mre11a(17535)
General description
MISSION® esiRNA are endoribonuclease prepared siRNA. They are a heterogeneous mixture of siRNA that all target the same mRNA sequence. These multiple silencing triggers lead to highly-specific and effective gene silencing.
For additional details as well as to view all available esiRNA options, please visit SigmaAldrich.com/esiRNA.
For additional details as well as to view all available esiRNA options, please visit SigmaAldrich.com/esiRNA.
Legal Information
MISSION is a registered trademark of Merck KGaA, Darmstadt, Germany
Storage Class
10 - Combustible liquids
flash_point_f
Not applicable
flash_point_c
Not applicable
Regulatory Information
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A Bakr et al.
Nucleic acids research, 43(6), 3154-3166 (2015-03-11)
Ataxia-telangiectasia mutated (ATM) is needed for the initiation of the double-strand break (DSB) repair by homologous recombination (HR). ATM triggers DSB end resection by stimulating the nucleolytic activity of CtIP and MRE11 to generate 3'-ssDNA overhangs, followed by RPA loading
Global Trade Item Number
| SKU | GTIN |
|---|---|
| EMU012341-20UG | 04061828472765 |
| EMU012341-50UG | 04061828247479 |