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Merck
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EMU033881

MISSION® esiRNA

targeting mouse Xrcc2

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About This Item

NACRES:
NA.51
UNSPSC Code:
41105324
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description

Powered by Eupheria Biotech

Quality Level

product line

MISSION®

form

lyophilized powder

esiRNA cDNA target sequence

AGAGCAGCCGGTTCTCATTAGTTTCACGTCATTTAAAAAGTAACAGTTTAAAAAAACACAGTTTTATGGTCAGAGAAAGTGGGGTGGAGTTTTGTTGATCTCTATCATCAAAAAGGCTTTTAGGTGCACTAAGGCAAGTCTTTAAAAGTCCTTTATAGGCTAAAGTGGTTTGATTCTAAAGTTTGTAATTCTGGGGAAATTAAATAGTACAGAAAAACTCGAAGCTGTTCTGTCCCCTTCAAGGTGTGGAAGGTCAGTCAGAACATGCTAAACTCCACCGAGCTTGTCTTGAAGCTCAAACCATGATACACATTTCAGACTAGGTCACTTTCTGCATACTTTAGGAAGGGTTCACCGCTGGTCCCTTGGCTCCTAGAGGCTGTGGCTGGAGAGAGTGCACAGAGCTGTTACTCTAATCAAAGGAAGACACACAGGGCCACCAGCTCATCTGCCTCCCTCAGGAAACTGGAATGAGCTGGGTG

Ensembl | mouse accession no.

NCBI accession no.

shipped in

ambient

storage temp.

−20°C

Gene Information

General description

MISSION® esiRNA are endoribonuclease prepared siRNA. They are a heterogeneous mixture of siRNA that all target the same mRNA sequence. These multiple silencing triggers lead to highly-specific and effective gene silencing.

For additional details as well as to view all available esiRNA options, please visit SigmaAldrich.com/esiRNA.

Legal Information

MISSION is a registered trademark of Merck KGaA, Darmstadt, Germany


Storage Class

10 - Combustible liquids

flash_point_f

Not applicable

flash_point_c

Not applicable

Regulatory Information

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Jennifer M Mason et al.
Cancer research, 74(13), 3546-3555 (2014-04-23)
RAD51 is the central protein that catalyzes DNA repair via homologous recombination, a process that ensures genomic stability. RAD51 protein is commonly expressed at high levels in cancer cells relative to their noncancerous precursors. High levels of RAD51 expression can
Xinzhu Deng et al.
PloS one, 10(6), e0127862-e0127862 (2015-06-30)
Mammalian NOTCH1-4 receptors are all associated with human malignancy, although exact roles remain enigmatic. Here we employ glp-1(ar202), a temperature-sensitive gain-of-function C. elegans NOTCH mutant, to delineate NOTCH-driven tumor responses to radiotherapy. At ≤20°C, glp-1(ar202) is wild-type, whereas at 25°C



Global Trade Item Number

SKUGTIN
EMU033881-20UG04061828515721
EMU033881-50UG04061828291373