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EMU043391

MISSION® esiRNA

targeting mouse Il17ra

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About This Item

NACRES:
NA.51
UNSPSC Code:
41105324
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description

Powered by Eupheria Biotech

Quality Level

100

product line

MISSION®

form

lyophilized powder

esiRNA cDNA target sequence

CCTGACTGTGAGGACAGCAAGATGAAGATGACTACCTCATGCGTGAGCTCAGGCAGCCTTTGGGATCCCAACATCACTGTGGAGACCTTGGACACACAGCATCTGCGAGTGGACTTCACCCTGTGGAATGAATCCACCCCCTACCAGGTCCTGCTGGAAAGTTTCTCCGACTCAGAGAACCACAGCTGCTTTGATGTCGTTAAACAAATATTTGCGCCCAGGCAAGAAGAATTCCATCAGCGAGCTAATGTCACATTCACTCTAAGCAAGTTTCACTGGTGCTGCCATCACCACGTGCAGGTCCAGCCCTTCTTCAGCAGCTGCCTAAATGACTGTTTGAGACACGCTGTGACTGTGCCCTGCCCAGTAATCTCAAATACCACAGTTCCCAAGCCAGTTGCAGACTACATTCCCCTGTGGGTGTATGGCCTCATCACACTCATCGCCATTCTGCTGGTGGGATCTGTCATCGTGCTGATCATCTGTATGACCTGGAGGCTTTCTGGCGCCGATCAAGAGAAACATGGTGATGACTCCAAAATCAATGGCA

Ensembl | mouse accession no.

ENSMUSG00000002897

NCBI accession no.

NM_008359

shipped in

ambient

storage temp.

−20°C

Gene Information

mouse ... IL17RA(16172), Il17ra(16172)

General description

MISSION® esiRNA are endoribonuclease prepared siRNA. They are a heterogeneous mixture of siRNA that all target the same mRNA sequence. These multiple silencing triggers lead to highly-specific and effective gene silencing.

For additional details as well as to view all available esiRNA options, please visit SigmaAldrich.com/esiRNA.

Legal Information

MISSION is a registered trademark of Merck KGaA, Darmstadt, Germany

Storage Class

12 - Non Combustible Liquids

flash_point_f

Not applicable

flash_point_c

Not applicable

Regulatory Information

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MHS
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Guoping Liu et al.
Clinical immunology (Orlando, Fla.), 154(2), 127-140 (2014-07-31)
IL-17, the hallmark cytokine of Th17 cells, plays a pivotal role in the pathogenesis of autoimmune diseases, including encephalomyelitis. In the central nervous system, neuroglial cells are the main residents that express IL-17R and respond to IL-17 by producing chemokines/cytokines

Global Trade Item Number

SKUGTIN
EMU043391-20UG04061828500437
EMU043391-50UG04061828274888