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EMU055431

MISSION® esiRNA

targeting mouse Fdxr

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NACRES:
NA.51
UNSPSC Code:
41105324
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description

Powered by Eupheria Biotech

Quality Level

100

product line

MISSION®

form

lyophilized powder

esiRNA cDNA target sequence

GCACCTGACCATCCTGAAGTAAAGAATGTTATCAACACATTTACACAGACAGCCCGCTCAGACCGCTGTGCCTTCCAGGGCAATGTGGTGGTGGGCAGGGACGTGTCGGTTCCAGAGCTTCGGGAAGCCTACCATGCTGTGGTGCTGAGTTATGGAGCAGAGGACCACCAACCCCTGGGAATTCCTGGCGAGGAGCTGCCTGGAGTGGTCTCAGCCCGGGCCTTTGTGGGCTGGTACAATGGACTTCCCGAGAACCAGGAGCTGGCGCCAGATCTGAGCTGTGACACGGCTGTAATTCTGGGACAGGGGAATGTGGCTCTGGATGTGGCCCGGATCCTGCTGACCCCACCTGAGCACCTGGAGAAAACAGACATCACAGAGGCTGCATTGGGGGCCCTGAGGCAGAGTCGGGTGAAGACTGTGTGGATAGTGGGCCGGCGTGGGCCCTTGCAAGTAGCGTTCACCATTAAGGAGCTTCGGGAGATGA

Ensembl | mouse accession no.

ENSMUSG00000018861

NCBI accession no.

NM_007997

shipped in

ambient

storage temp.

−20°C

Gene Information

mouse ... FDXR(14149), Fdxr(14149)

General description

MISSION® esiRNA are endoribonuclease prepared siRNA. They are a heterogeneous mixture of siRNA that all target the same mRNA sequence. These multiple silencing triggers lead to highly-specific and effective gene silencing.

For additional details as well as to view all available esiRNA options, please visit SigmaAldrich.com/esiRNA.

Legal Information

MISSION is a registered trademark of Merck KGaA, Darmstadt, Germany

Storage Class

10 - Combustible liquids

flash_point_f

Not applicable

flash_point_c

Not applicable

Regulatory Information

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Valerie N Barton et al.
Molecular cancer therapeutics, 14(3), 769-778 (2015-02-26)
Triple-negative breast cancer (TNBC) has the lowest 5-year survival rate of invasive breast carcinomas, and currently there are no approved targeted therapies for this aggressive form of the disease. The androgen receptor (AR) is expressed in up to one third
Luofu Wang et al.
PloS one, 9(5), e96586-e96586 (2014-05-07)
The objective of this study was to investigate nanobubbles carrying androgen receptor (AR) siRNA and their in vitro and in vivo anti-tumor effects, when combined with ultrasonic irradiation, on androgen-independent prostate cancer (AIPC). Nanobubbles carrying AR siRNA were prepared using
Tao Shan et al.
Cancer science, 105(7), 847-856 (2014-05-13)
Norepinephrine and epinephrine, catecholamine hormones that are major mediators for chronic stress-induced cancers, are implicated in the progression of a number of cancer cells, including gastric adenocarcinoma. However, the underlying mechanisms of these hormones have not been well elucidated. Epithelial-mesenchymal
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Global Trade Item Number

SKUGTIN
EMU055431-20UG04061828468010
EMU055431-50UG04061828242672