EMU061791
MISSION® esiRNA
targeting mouse Ptpn1
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About This Item
NACRES:
NA.51
UNSPSC Code:
41105324
description
Powered by Eupheria Biotech
Quality Level
product line
MISSION®
form
lyophilized powder
esiRNA cDNA target sequence
CGGAACAGGTACCGAGATGTCAGCCCTTTTGACCACAGTCGGATTAAATTGCACCAGGAAGATAATGACTATATCAATGCCAGCTTGATAAAAATGGAAGAAGCCCAGAGGAGCTATATTCTCACCCAGGGCCCTTTACCAAACACATGTGGGCACTTCTGGGAGATGGTGTGGGAGCAGAAGAGCAGGGGCGTGGTCATGCTCAACCGCATCATGGAGAAAGGCTCGTTAAAATGTGCCCAGTATTGGCCACAGCAAGAAGAAAAGGAGATGGTCTTTGATGACACAGGTTTGAAGTTGACACTAATCTCTGAAGATGTCAAGTCATATTACACAGTACGACAGTTGGAGTTGGAAAACCTGACTACCAAGGAGACTCGAGAGATCCTGCCTTTCCACTACACC
Ensembl | mouse accession no.
NCBI accession no.
shipped in
ambient
storage temp.
−20°C
Gene Information
mouse ... PTPN1(19246), Ptpn1(19246)
General description
MISSION® esiRNA are endoribonuclease prepared siRNA. They are a heterogeneous mixture of siRNA that all target the same mRNA sequence. These multiple silencing triggers lead to highly-specific and effective gene silencing.
For additional details as well as to view all available esiRNA options, please visit SigmaAldrich.com/esiRNA.
For additional details as well as to view all available esiRNA options, please visit SigmaAldrich.com/esiRNA.
Legal Information
MISSION is a registered trademark of Merck KGaA, Darmstadt, Germany
Storage Class
10 - Combustible liquids
flash_point_f
Not applicable
flash_point_c
Not applicable
Regulatory Information
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Liza D Morales et al.
PloS one, 9(5), e97104-e97104 (2014-05-09)
To maintain tissue homeostasis, apoptosis is functionally linked to the cell cycle through the retinoblastoma (Rb)/E2F pathway. When the Rb tumor suppressor protein is functionally inactivated, E2F1 elicits an apoptotic response through both intrinsic (caspase-9 mediated) and extrinsic (caspase-8 mediated)
Xiaoyan Zhang et al.
Scientific reports, 5, 12987-12987 (2015-08-12)
Renal mesangial cells (RMCs) constitute a population of cells in glomerular mesangium. Inflammatory cytokines produced by RMCs play a vital role in renal inflammation. miRNAs are key regulators of inflammatory cytokine expression. The abnormal expression of renal miRNAs and the
Global Trade Item Number
| SKU | GTIN |
|---|---|
| EMU061791-20UG | 04061828489404 |
| EMU061791-50UG | 04061828264131 |