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EMU093101

MISSION® esiRNA

targeting mouse Arhgap4

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About This Item

NACRES:
NA.51
UNSPSC Code:
41105324
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description

Powered by Eupheria Biotech

Quality Level

product line

MISSION®

form

lyophilized powder

esiRNA cDNA target sequence

GCAGCATCAGCAAAAACAAAGTCTTCTCCCGGGGACCTGGGGCTCCAATTTCCCCCTCAACCTCCCATCCCCAGGGTCCAGATTCAACTCGCAAGCCAGTCTGAGGCAGCTTACCTCCAGCAGCCACCACCAAGCCCACCATTCCACATAGGCCTATTGCTTCACCTCAGCCCTCTTCTAGGTCTCTTGGGAGGTAGCAAAGGAAGGAAGCTGGAGATGAGCTCCTCTTATGCCTTTGCTTGGAAGCCTTGGGCTGTGGCTGTGAAATATGGAAGTGGCAGTAATTCATAAAGACCCCATGTGCTGGTTGCTGTTGTAATAGCCTGTGCTGTTTGGGGGGCGCTGAACAGGTAGGGTGCAGGGCAACTCCCAGAGCCTGCACTGCTAGAGACCAGATGCCAA

Ensembl | mouse accession no.

NCBI accession no.

shipped in

ambient

storage temp.

−20°C

Gene Information

General description

MISSION® esiRNA are endoribonuclease prepared siRNA. They are a heterogeneous mixture of siRNA that all target the same mRNA sequence. These multiple silencing triggers lead to highly-specific and effective gene silencing.

For additional details as well as to view all available esiRNA options, please visit SigmaAldrich.com/esiRNA.

Legal Information

MISSION is a registered trademark of Merck KGaA, Darmstadt, Germany


Storage Class

10 - Combustible liquids

flash_point_f

Not applicable

flash_point_c

Not applicable

Regulatory Information

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Jennifer Munkley et al.
Oncotarget, 6(33), 34358-34374 (2015-10-10)
Patterns of glycosylation are important in cancer, but the molecular mechanisms that drive changes are often poorly understood. The androgen receptor drives prostate cancer (PCa) development and progression to lethal metastatic castration-resistant disease. Here we used RNA-Seq coupled with bioinformatic
Na Li et al.
Nature cell biology, 16(11), 1080-1091 (2014-10-27)
Cyclin C was cloned as a growth-promoting G1 cyclin, and was also shown to regulate gene transcription. Here we report that in vivo cyclin C acts as a haploinsufficient tumour suppressor, by controlling Notch1 oncogene levels. Cyclin C activates an



Global Trade Item Number

SKUGTIN
EMU093101-20UG04061828531479
EMU093101-50UG04061828869305