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EMU173751

MISSION® esiRNA

targeting mouse Hnrnpc

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About This Item

NACRES:
NA.51
UNSPSC Code:
41105324
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description

Powered by Eupheria Biotech

Quality Level

100

product line

MISSION®

form

lyophilized powder

esiRNA cDNA target sequence

GCGGTCTCTTCTCTCTCTCCTTCCTTTTGTGAGATTTTTTTGATCTTCAGCTACATTTTCAGCTTTGTGAGAAACCTCATCATCAAAGGAGATGGCTAGCAATGTTACCAACAAGACAGATCCTCGGTCCATGAATTCCCGTGTATTCATTGGGAATCTCAACACTCTGGTGGTCAAGAAGTCTGATGTGGAGGCCATCTTTTCAAAGTATGGCAAAATTGTGGGCTGCTCTGTGCATAAAGGCTTTGCCTTTGTCCAGTATGTTAATGAAAGAAATGCCCGAGCTGCTGTAGCTGGCGAGGATGGCAGAATGATTGCTGGCCAGGTTTTAGATATTAACCTGGCTGCAGAGCCAAAAGTGAACCGAGGAAAAGCAGGTGTGAAACGATCTGCAGCGGAGATGTACGGGTCAGTACCAGAACACCCTTCTCCGTCCCCTCTACTCAGTTCCTCATTTGACTTGGACTATGACTTTCAACGGGATTATTATGACAGGATGTACAGTTACCCAGCG

Ensembl | mouse accession no.

ENSMUSG00000060373

NCBI accession no.

NM_016884

shipped in

ambient

storage temp.

−20°C

Gene Information

mouse ... HNRNPC(15381), Hnrnpc(15381)

General description

MISSION® esiRNA are endoribonuclease prepared siRNA. They are a heterogeneous mixture of siRNA that all target the same mRNA sequence. These multiple silencing triggers lead to highly-specific and effective gene silencing.

For additional details as well as to view all available esiRNA options, please visit SigmaAldrich.com/esiRNA.

Legal Information

MISSION is a registered trademark of Merck KGaA, Darmstadt, Germany

Storage Class

10 - Combustible liquids

flash_point_f

Not applicable

flash_point_c

Not applicable

Regulatory Information

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Zuzana Cieniková et al.
RNA (New York, N.Y.), 21(11), 1931-1942 (2015-09-16)
The human hnRNP C is a ubiquitous cellular protein involved in mRNA maturation. Recently, we have shown that this protein specifically recognizes uridine (U) pentamers through its single RNA recognition motif (RRM). However, a large fraction of natural RNA targets
Na Li et al.
Nature cell biology, 16(11), 1080-1091 (2014-10-27)
Cyclin C was cloned as a growth-promoting G1 cyclin, and was also shown to regulate gene transcription. Here we report that in vivo cyclin C acts as a haploinsufficient tumour suppressor, by controlling Notch1 oncogene levels. Cyclin C activates an

Global Trade Item Number

SKUGTIN
EMU173751-20UG04061831391473
EMU173751-50UG04061828708192