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F1141

Bovine Fibronectin

from bovine plasma, liquid, suitable for cell culture

Synonym(s):

Fibronectin

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About This Item

UNSPSC Code:
12352202
eCl@ss:
42020141
NACRES:
NA.75
EC Number:
289-149-2
MDL number:
MFCD00131062
Biological source:
bovine plasma
Form:
solution
Technique(s):
cell culture | mammalian: suitable
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Product Name

Fibronectin bovine plasma, solution, sterile-filtered, BioReagent, suitable for cell culture

biological source

bovine plasma

sterility

sterile-filtered

product line

BioReagent

form

solution

packaging

pkg of 1 mg, pkg of 2 mg, pkg of 5 mg

technique(s)

cell culture | mammalian: suitable

surface coverage

1‑5 μg/cm2

UniProt accession no.

P07589

binding specificity

Peptide Source: Collagen
, Peptide Source: Fibrinogen

shipped in

wet ice

storage temp.

2-8°C

Gene Information

bovine ... FN1(280794)

General description

Fibronectin is a ubiquitous protein of the extracellular matrix. It is a mosaic protein, that is made up of three types of repeating modular consensus amino acid sequences. Fibronectins belongs to a class of high-molecular-weight glycoproteins. Cellular fibronectin is expressed by fibroblasts and plasma fibronectin is usually liberated by hepatocytes.

Application

Fibronectin (FN) bovine plasma has been used in:
  • fibronectin and adsorption analysis (ELISA (enzyme-linked immunosorbent assay))
  • transwell migration
  • fibronectin assay

Biochem/physiol Actions

Fibronectins participate in cell adhesion, cytoskeletal organization, oncogenic transformation, cell migration, phagocytosis, hemostasis, and embryonic differentiation.

Analysis Note

Protein homogeneity is evaluated by immunoelectrophoresis.

Other Notes

Product F1141, Fibronectin from bovine plasma is a solution in 0.05 M TBS pH 7.5.

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pictograms

Health hazard
GHS08

signalword

Danger

hcodes

H317,H334

Hazard Classifications

Resp. Sens. 1 - Skin Sens. 1

Storage Class

12 - Non Combustible Liquids

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves

Regulatory Information

监管及禁止进口产品

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Certificates of Analysis (COA)

Lot/Batch Number
SLCG8374
SLCD2908
SLBZ7025
SLBZ5423
SLBX5503

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Protocols

Fibronectin Coating Protocol

Dilute fibronectin for cell attachment, varying per cell type. Coating protocol, products, and FAQs provided.

Articles

3D 细胞培养工具和技术

3D细胞培养概述。了解2D与3D细胞培养的对比结果，3D细胞培养的优势以及可用于开发3D细胞模型的技术

什么是细胞外基质？

细胞外基质（ECM）是由细胞分泌并在组织中围绕在其周围。

纤连蛋白

纤连蛋白（FN）是由肝细胞产生的多功能细胞外基质糖蛋白，以接近微摩尔的浓度循环，并与局部产生的细胞FN一起在细胞表面组装成胞外基质原纤维。

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Chesley's Hypertensive Disorders in Pregnancy, 221-251 (2015)
Role of subnano-, nano-and submicron-surface features on osteoblast differentiation of bone marrow mesenchymal stem cells
Khang D, et al.
Biomaterials, 33(26), 5997-6007 (2012)
CCL2/CCR2 chemokine signaling coordinates survival and motility of breast cancer cells through Smad3 and p42/44MAPK dependent mechanisms
Fang W B, et al.
The Journal of biological chemistry, jbc-M112 (2012)
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Global Trade Item Number

SKUGTIN
F1141-1MG04061835568444
F1141-2MG04061833611678
F1141-5MG04061835514144