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Merck
CN

F5881

Freund′s Adjuvant, Complete

cell suspension

Synonym(s):

FCA

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About This Item

UNSPSC Code:
12352203
NACRES:
NA.46
MDL number:
Technical Service
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form

cell suspension

Quality Level

color

amber

storage temp.

2-8°C

General description

Each mL of Complete Freund′s adjuvant contains 1 mg of Mycobacterium tuberculosis (H37Ra, ATCC 25177), heat killed and dried, 0.85 mL paraffin oil and 0.15 mL mannide monooleate.

Application

Antigens (preferably in saline) are typically mixed with an equal volume of the adjuvant to form an emulsion.
Freund′s Adjuvants may be used to produce water-in-oil emulsions of immunogens. Antigens in water-in-oil emulsions stimulate high and long-lasting antibody responses which can be attributed to the slow release of antigen.

Biochem/physiol Actions

The mycobacteria in Complete Freund′s adjuvant attracts macrophages and other cells to the injection site which enhances the immune response. For this reason, Complete Freund′s Adjuvant is used for initial injections and Incomplete Freund′s Adjuvant for subsequent boosts.

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.


Storage Class

10 - Combustible liquids

flash_point_f

Not applicable

flash_point_c

Not applicable

Regulatory Information

常规特殊物品
常规特殊物品

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Articles

抗体可与特定的抗原结合,产生独特的抗体-抗原复合物。本文讨论这一连接键的性质,以及其作为分子标签的研究应用。

Antibodies combine with specific antigens to generate an exclusive antibody-antigen complex. Learn about the nature of this bond and its use as a molecular tag for research.

Related Content

Access high-quality reagents for antibody workflows, including adjuvants, blocking reagents, conjugation kits, and more.


Kasper D Kristensen et al.
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Sukjae Joshua Kang et al.
The Korean journal of physiology & pharmacology : official journal of the Korean Physiological Society and the Korean Society of Pharmacology, 21(5), 487-493 (2017-09-09)
The anterior cingulate cortex (ACC) is known for its role in perception of nociceptive signals and the associated emotional responses. Recent optogenetic studies, involving modulation of neuronal activity in the ACC, show that the ACC can modulate mechanical hyperalgesia. In
E L Brown et al.
Clinical microbiology and infection : the official publication of the European Society of Clinical Microbiology and Infectious Diseases, 15(2), 156-164 (2009-01-22)
Methicillin-resistant Staphylococcus aureus is increasingly responsible for staphylococcal infections in the community. A large percentage of the community-acquired methicillin-resistant (CA-MRSA) strains in the USA produce Panton-Valentine leukocidin (PVL), which is associated with severe infections. The virulence of the clinical CA-MRSA



Global Trade Item Number

SKUGTIN
F5881-6X10ML04061838255471
F5881-10ML04061838255457
F5881-10X10ML04061838255464