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G4626

L-Glutathione oxidized disodium salt

Name: <SC>L</SC>-Glutathione oxidized disodium salt
Brand: SIGMA

≥98%, suitable for HPLC

Synonym(s):

GSSG

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About This Item

Empirical Formula (Hill Notation):

C₂₀H₃₀N₆Na₂O₁₂S₂

CAS Number:

103239-24-3

Molecular Weight:

656.59

MDL number:

MFCD00148894

UNSPSC Code:

12352209

PubChem Substance ID:

24895179

NACRES:

NA.26

Beilstein/REAXYS Number:

6265389

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Properties

Product Name

L-Glutathione oxidized disodium salt, ≥98%, powder

Quality Level

200

assay

≥98%

form

powder

technique(s)

HPLC: suitable

impurities

ethanol, essentially free

color

white to off-white

storage temp.

−20°C

SMILES string

[Na+].[Na+].N[C@@H](CCC(=O)N[C@@H](CSSC[C@H](NC(=O)CC[C@H](N)C([O-])=O)C(=O)NCC(O)=O)C(=O)NCC([O-])=O)C(O)=O

InChI

1S/C20H32N6O12S2.2Na/c21-9(19(35)36)1-3-13(27)25-11(17(33)23-5-15(29)30)7-39-40-8-12(18(34)24-6-16(31)32)26-14(28)4-2-10(22)20(37)38;;/h9-12H,1-8,21-22H2,(H,23,33)(H,24,34)(H,25,27)(H,26,28)(H,29,30)(H,31,32)(H,35,36)(H,37,38);;/q;2*+1/p-2/t9-,10-,11-,12-;;/m0../s1

InChI key

DRFILBXQKYDTFW-JIWRMXRASA-L

Description

Application

L-Glutathione oxidized disodium salt has been used in 5,5′-dithiobis-(2-nitrobenzoic acid) (DTNB)/glutathione reductase enzyme recycling method to determine plasma or tissue glutathione levels. It has also been used in NADPH-dependent glutathione disulfide reduction assay.

Biochem/physiol Actions

Oxidized L-glutathione is frequently measured in vivo as an indicator of oxidative stress. Oxidized L-Glutathione may be converted to L-glutathione by various reducing systems.

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Storage Class

11 - Combustible Solids

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

Regulatory Information

动植物源性产品

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Methods for the Determination of Plasma or Tissue Glutathione Levels

Trent E, et.al

Methods in Molecular Biology, 889, 315-324 (2012)

Dietary methionine can sustain cytosolic redox homeostasis in the mouse liver

Sofi Eriksson

Nature Communications (2015)

Oxidized forms of glutathione in peripheral blood as biomarkers of oxidative stress.

Rossi R

Clinical Chemistry, 52(7), 1406-1414 (2006)

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Global Trade Item Number

SKU	GTIN
G4626-100MG	04061835545186
G4626-5G	04061833611043
G4626-1G	04061835545193
G4626-250MG	04061835545209
G4626-500MG	04061833271292