G4875
D-(+)-Glucosamine hydrochloride
≥99% (HPLC), powder
Synonym(s):
2-Amino-2-deoxy-D-glucose hydrochloride, Chitosamine hydrochloride
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About This Item
Empirical Formula (Hill Notation):
C6H13NO5 · HCl
CAS Number:
Molecular Weight:
215.63
PubChem Substance ID:
UNSPSC Code:
12352201
MDL number:
NACRES:
NA.25
EC Number:
200-638-1
Beilstein/REAXYS Number:
4157370
biological source
Aspergillus niger
Quality Level
assay
≥99% (HPLC)
form
powder
technique(s)
HPLC: suitable
color
white
mp
190-194 °C (dec.) (lit.)
solubility
water: 100 mg/mL, clear, colorless
storage temp.
room temp
SMILES string
Cl.N[C@H]1C(O)O[C@H](CO)[C@@H](O)[C@@H]1O
InChI
1S/C6H13NO5.ClH/c7-3-5(10)4(9)2(1-8)12-6(3)11;/h2-6,8-11H,1,7H2;1H/t2-,3-,4-,5-,6?;/m1./s1
InChI key
QKPLRMLTKYXDST-NSEZLWDYSA-N
Application
D-(+)-Glucosamine hydrochloride has been used:
- as a standard to quantify and express chitin content as glucosamine equivalents.
- to stimulate cells with glucose in the presence of glucosamine
Biochem/physiol Actions
Glucosamine, an amino sugar, is the precursor of the hexosamine biosynthetic pathway leading to the formation of UDP-N-acetylglucosamine (UDP-GlcNAc), which is then used for making glycosaminoglycans, proteoglycans, and glycolipids. D-(+)-Glucosamine inhibits the coaggregation of Candida yeast species with the bacterial strain S. salivarius.
Other Notes
To gain a comprehensive understanding of our extensive range of Monosaccharides for your research, we encourage you to visit our Carbohydrates Category page.
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Storage Class
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type N95 (US)
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Luana C Farnesi et al.
PloS one, 7(1), e30363-e30363 (2012-02-01)
Population control of the dengue vector mosquito, Aedes aegypti, is difficult due to many reasons, one being the development of resistance to neurotoxic insecticides employed. The biosynthesis of chitin, a major constituent of insect cuticle, is a novel target for
Chao Yang et al.
The Plant cell, 31(1), 172-188 (2019-01-06)
To defend against pathogens, plants have developed complex immune systems, including plasma membrane receptors that recognize pathogen-associated molecular patterns, such as chitin from fungal cell walls, and mount a defense response. Here, we identify a chitinase, MoChia1 (Magnaporthe oryzae chitinase
Yang Ge et al.
PloS one, 14(4), e0215834-e0215834 (2019-04-24)
Pear psylla, Cacopsylla chinensis (Yang & Li) are present as two seasonal morphotypes in pear orchards where they, suck phloem sap, defoliate pear trees, and cause fruit russet. Despite the importance of natural enemies in psyllid control, the interactions between
Global Trade Item Number
| SKU | GTIN |
|---|---|
| G4875-1KG | 04061833632192 |
| G4875-500G | 04061833632215 |
| G4875-10MG | 04061835366811 |
| G4875-25G | 04061833632208 |
| G4875-100G | 04061835366804 |