G6019
Glyceraldehyde-3-phosphate Dehydrogenase from human erythrocytes
lyophilized powder, 50-150 units/mg protein
Synonym(s):
D-Glyceraldehyde 3-phosphate:NAD+ oxidoreductase (phosphorylating), GAPDH
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About This Item
CAS Number:
UNSPSC Code:
12352204
NACRES:
NA.54
MDL number:
Specific activity:
50-150 units/mg protein
form
lyophilized powder
Quality Level
specific activity
50-150 units/mg protein
composition
Protein, 40-70% biuret
UniProt accession no.
foreign activity
3-Phosphoglyceric phosphokinase ≤2%
storage temp.
−20°C
Gene Information
human ... GAPDH(2597)
Biochem/physiol Actions
Glyceraldehyde-3-phosphate dehydrogenase catalyzes the conversion of glyceraldehyde-3-phosphate to 1,3-bisphosphoglycerate as part of glycolysis. It has also been shown to have roles in initiation of apoptosis, transcription activation and the shuttling of ER to Golgi vesicles<<<18,New>>>.
Physical form
Lyophilized powder containing sodium citrate buffer salts
Other Notes
One unit will reduce 1.0 μmole of 3-phosphoglycerate to D-glyceraldehyde 3-phosphate per min in a coupled system with 3-phosphoglyceric phosphokinase at pH 7.6 at 25 °C.
Storage Class
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
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Articles
本页面介绍了一篇有关瓦博格效应的文章，以及其如何能够在正常氧气水平下，增强肿瘤细胞中葡萄糖向乳酸的转化。Otto Heinrich Warburg在1924年证明，癌细胞显示出对糖酵解的依赖性增加，以满足他们的能量需求，无论是否有充足的氧气存在。
Warburg effect enhances glucose to lactate conversion in tumor cells, regardless of oxygen levels; impacting cancer metabolism since 1924.
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Global Trade Item Number
| SKU | GTIN |
|---|---|
| G6019-100UN | 04061833638767 |