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Merck
CN

H1252

Homovanillic acid

>99% purity (TLC), powder

Synonym(s):

4-Hydroxy-3-methoxyphenylacetic acid, HVA

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About This Item

Linear Formula:
HOC6H3(OCH3)CH2CO2H
CAS Number:
Molecular Weight:
182.17
NACRES:
NA.47
PubChem Substance ID:
UNSPSC Code:
12171500
EC Number:
206-176-7
MDL number:
Beilstein/REAXYS Number:
2213447
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Product Name

Homovanillic acid, Fluorimetric reagent

Quality Level

assay

>99% (TLC)

form

powder

technique(s)

titration: suitable

color

white to off-white

mp

142-145 °C (lit.)

solubility

ethanol: 50 mg/mL, colorless to light yellow

application(s)

diagnostic assay manufacturing
hematology
histology

storage temp.

room temp

SMILES string

COc1cc(CC(O)=O)ccc1O

InChI

1S/C9H10O4/c1-13-8-4-6(5-9(11)12)2-3-7(8)10/h2-4,10H,5H2,1H3,(H,11,12)

InChI key

QRMZSPFSDQBLIX-UHFFFAOYSA-N

Application

Homovanillic acid has been used as a standard in HPLC analysis.

Biochem/physiol Actions

Metabolite of dihydroxyphenylacetic acid (DOPAC) by catechol O-methyltransferase; reagent for the fluorimetric determination of glucose oxidase and other oxidative enzymes.


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Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

dust mask type N95 (US), Eyeshields, Gloves



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Practical Fluorescence (1990)
Forced nonuse in unilateral parkinsonian rats exacerbates injury.
Tillerson JL
The Journal of Neuroscience, 22, 6790-6790 (2002)
Tashjian AH and Armstrong EJ
Principles of Pharmacology: The Pathophysiologic Basis of Drug Therapy (2011)



Global Trade Item Number

SKUGTIN
H1252-100MG04061832343150
H1252-1G04061833664773
H1252-250MG04061833664780