Skip to Content
Merck
CN

Key Documents

View All Documentation

H1635

N-Hippuryl-His-Leu hydrate

chromogenic, ≥98% (HPLC), powder

Synonym(s):

N-Benzoyl-Gly-His-Leu, N-Hippuryl-L-histidyl-L-leucine hydrate

Sign In to View Organizational & Contract Pricing.

Select a Size

Change View

About This Item

Empirical Formula (Hill Notation):
C21H27N5O5 · xH2O
CAS Number:
207386-83-2
Molecular Weight:
429.47 (anhydrous basis)
NACRES:
NA.32
PubChem Substance ID:
24895469
UNSPSC Code:
12352204
EC Number:
250-597-9
MDL number:
MFCD00149318
Beilstein/REAXYS Number:
5664178
Technical Service
Need help? Our team of experienced scientists is here for you.
Let Us Assist

Product Name

N-Hippuryl-His-Leu hydrate, powder, ≥98% (HPLC)

Quality Level

200

assay

≥98% (HPLC)

form

powder

color

white to off-white

solubility

acetic acid: ~50 mg/mL

storage temp.

−20°C

SMILES string

O.CC(C)C[C@H](NC(=O)[C@H](Cc1c[nH]cn1)NC(=O)CNC(=O)c2ccccc2)C(O)=O

InChI

1S/C21H27N5O5.H2O/c1-13(2)8-17(21(30)31)26-20(29)16(9-15-10-22-12-24-15)25-18(27)11-23-19(28)14-6-4-3-5-7-14;/h3-7,10,12-13,16-17H,8-9,11H2,1-2H3,(H,22,24)(H,23,28)(H,25,27)(H,26,29)(H,30,31);1H2/t16-,17-;/m0./s1

InChI key

NWOJMNXIJBZMPK-QJHJCNPRSA-N

Gene Information

human ... ACE(1636), ACE2(59272)
mouse ... ACE3(217246)
rat ... ACE(11421), ACE2(70008), ACE3(498012)

General description

Substrate for angiotensin converting enzyme.

Application

N-Hippuryl-His-Leu hydrate has been used in the measurement of angiotensin-converting enzyme (ACE) inhibitory activity using oyster hydrolysates, semimembranosus muscle samples, and rabbit lung acetone powder.

Biochem/physiol Actions

N-Hippuryl-His-Leu hydrate (HHL) can be used as an artificial substrate for angiotensin-converting enzyme (ACE).

Still not finding the right product?

Explore all of our products under N-Hippuryl-His-Leu hydrate

Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

Choose from one of the most recent versions:

Certificates of Analysis (COA)

Lot/Batch Number
SLCG7087
SLBW5368
SLBR2049V
SLBK2049V
118K5006V

Don't see the Right Version?

If you require a particular version, you can look up a specific certificate by the Lot or Batch number.

Search for a COA

Already Own This Product?

Find documentation for the products that you have recently purchased in the Document Library.

Visit the Document Library

N Nahariah et al.
Asian-Australasian journal of animal sciences, 28(6), 855-861 (2015-02-27)
Lactobacillus plantarum is used for fermentation of fish products, meat and milk. However, the utilization of these bacteria in egg processing has not been done. This study was designed to evaluate the potential of fermented egg albumen as a functional
Darcy R Flora et al.
Endocrinology, 151(6), 2769-2776 (2010-04-13)
Natriuretic peptide receptor-A (NPR-A), also known as guanylyl cyclase-A, is a transmembrane receptor guanylyl cyclase that is activated by the cardiac hormones atrial natriuretic peptide and B-type natriuretic peptide. Although ligand-dependent NPR-A degradation (also known as down-regulation) is widely acknowledged
A Tiengo et al.
Journal of food science, 74(5), H121-H126 (2009-08-04)
Amaranth seeds have been considered as an excellent alternative or complementary source of food protein due to their balanced amino acid composition. However, their potential as a source of bioactive peptides has not been explored. The present study is aimed
View All Related Papers

Global Trade Item Number

SKUGTIN
H1635-100MG04061835545438
H1635-1G04061833672686
H1635-25MG04061835557080
H1635-500MG04061835512607