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H4884

Hippuryl-His-Leu acetate salt

Name: Hippuryl-His-Leu acetate salt
Brand: SIGMA

≥98% (HPLC), angiotensin converting enzyme substrate, powder

Synonym(s):

N-Benzoyl-Gly-His-Leu

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About This Item

Empirical Formula (Hill Notation):

C₂₁H₂₇N₅O₅

CAS Number:

103404-54-2

Molecular Weight:

429.47

UNSPSC Code:

12352200

PubChem Substance ID:

329815212

NACRES:

NA.32

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Properties

Product Name

Hippuryl-His-Leu acetate salt,

assay

≥98% (HPLC)

Quality Level

200

form

powder

solubility

acetic acid: 50 mg/mL, clear, colorless to very faintly yellow

storage temp.

−20°C

SMILES string

CC(O)=O.CC(C)C[C@H](NC(=O)[C@H](Cc1c[nH]cn1)NC(=O)CNC(=O)c2ccccc2)C(O)=O

InChI

1S/C21H27N5O5.C2H4O2/c1-13(2)8-17(21(30)31)26-20(29)16(9-15-10-22-12-24-15)25-18(27)11-23-19(28)14-6-4-3-5-7-14;1-2(3)4/h3-7,10,12-13,16-17H,8-9,11H2,1-2H3,(H,22,24)(H,23,28)(H,25,27)(H,26,29)(H,30,31);1H3,(H,3,4)/t16-,17-;/m0./s1

InChI key

NSEVQQKNHZCIKL-QJHJCNPRSA-N

Gene Information

human ... ACE(1636), ACE2(59272)
mouse ... ACE3(217246)
rat ... ACE(11421), ACE2(70008), ACE3(498012)

Description

Biochem/physiol Actions

Substrate for angiotensin converting enzyme.

Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

Regulatory Information

常规特殊物品

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Inhibition of angiotensin converting enzyme (ACE) activity by flavan-3-ols and procyanidins.

Lucas Actis-Goretta et al.

FEBS letters, 555(3), 597-600 (2003-12-17)

It was determined that flavan-3-ols and procyanidins have an inhibitory effect on angiotensin I converting enzyme (ACE) activity, and the effect was dependent on the number of epicatechin units forming the procyanidin. The inhibition by flavan-3-ols and procyanidins was competitive

Emblicanin rich Emblica officinalis extract encapsulated double emulsion: controlled release of bioactive during phagocytosis and in vitro digestion.

Neha Chaudhary et al.

Journal of food science and technology, 57(4), 1371-1381 (2020-03-18)

Controlled release of Emblicanin rich water soluble extract of Emblica officinalis (EEO) from the inner phase of water-in-oil-in-water type double emulsion (DE), during in vitro digestion and phagocytosis was investigated. It was observed that release of EEO (measured as total polyphenols

Mammalian Genome null

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Global Trade Item Number

SKU	GTIN
H4884-100MG	04061833796405
H4884-1G	04061833796412
H4884-25MG	04061833796450
H4884-500MG	04061833796467