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Merck
CN

H7750

DL-Histidine

≥99% (TLC), suitable for ligand binding assays

Synonym(s):

(±)-2-Amino-3-(4-imidazolyl)propionic acid

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About This Item

Empirical Formula (Hill Notation):
C6H9N3O2
CAS Number:
Molecular Weight:
155.15
NACRES:
NA.26
PubChem Substance ID:
eCl@ss:
32160406
UNSPSC Code:
12352209
EC Number:
225-660-9
MDL number:
Beilstein/REAXYS Number:
7800
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Product Name

DL-Histidine, ≥99% (TLC)

Quality Level

assay

≥99% (TLC)

form

powder

technique(s)

ligand binding assay: suitable

mp

273 °C (dec.) (lit.)

solubility

0.5 M HCl: soluble

application(s)

peptide synthesis

SMILES string

NC(Cc1c[nH]cn1)C(O)=O

InChI

1S/C6H9N3O2/c7-5(6(10)11)1-4-2-8-3-9-4/h2-3,5H,1,7H2,(H,8,9)(H,10,11)

InChI key

HNDVDQJCIGZPNO-UHFFFAOYSA-N

Application

DL-Histidine has been used to study the fouling behaviour of polyethersulfone ultrafiltration membranes made with different PVP (polyvinylpyrrolidone).
DL-Histidine is the mixed isomer of D- and L-histidine. DL-Histidine may be used to evaluate the efficiency of amino acid chiral ligand exchange media and systems and in running buffers for capillary electrophoresis.

Biochem/physiol Actions

L-Histidine is involved in the one-carbon unit metabolism. It is associated with protein methylation. L-Histidine is a part of hemoglobin structure and function. L-Histidine is a component of dipeptides with antioxidative property. Histidine serves as a precursor for the formation of histamine, which is associated with allergic responses. Urocanic acid, an immune response modulator in skin is also biosynthesised from histidine.


Storage Class

11 - Combustible Solids

wgk

WGK 1

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)



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Fouling behaviour of polyethersulfone UF membranes made with different PVP
J.Marchese
Journal of Membrane Science , 211, 1-11 (2009)
Tetsuya Chujo et al.
PloS one, 9(6), e98737-e98737 (2014-06-04)
WRKY transcription factors and mitogen-activated protein kinase (MAPK) cascades have been shown to play pivotal roles in the regulation of plant defense responses. We previously reported that OsWRKY53-overexpressing rice plants showed enhanced resistance to the rice blast fungus. In this
Hai Zhou et al.
Nature communications, 5, 4884-4884 (2014-09-12)
Thermosensitive genic male-sterile (TGMS) lines, which are male-sterile at restrictive (high) temperatures but male-fertile at permissive (low) temperatures, have been widely used in breeding two-line hybrid rice (Oryza sativa L.). Here we find that mutation of thermosensitive genic male sterile



Global Trade Item Number

SKUGTIN
H7750-100G04061832722733
H7750-25G04061833804353