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Merck
CN

H7891

Hexammine cobalt(III) chloride

for use in transformations, X-ray crystallography and NMR

Synonym(s):

Cobalt hexammine trichloride, Hexaamminecobalt trichloride

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About This Item

Linear Formula:
[Co(NH3)6]Cl3
CAS Number:
Molecular Weight:
267.48
NACRES:
NA.52
PubChem Substance ID:
UNSPSC Code:
12352200
EC Number:
234-103-9
MDL number:
Technical Service
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grade

Molecular Biology

Quality Level

form

powder

storage temp.

room temp

SMILES string

N.N.N.N.N.N.[Cl-].[Cl-].[Cl-].[Co+3]

InChI

1S/3ClH.Co.6H3N/h3*1H;;6*1H3/q;;;+3;;;;;;/p-3

InChI key

JXBGZYGSWFSYFI-UHFFFAOYSA-K

General description

Hexammine cobalt(III) is considered an analog of fully solvated magnesium, capable of activating some enzymes that requires magnesium. It is useful in DNA condensation studies.

Application

Suitable for
  • DNA condensation studies
  • induction of transitions of DNA from B to A or Z forms
  • induction of nucleic acid crystal growth
  • stabilization of tertiary tRNA interactions
  • preparation of ligation buffer


pictograms

Health hazard

signalword

Danger

Hazard Classifications

Aquatic Chronic 4 - Carc. 2 - Resp. Sens. 1 - Skin Sens. 1

Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

dust mask type N95 (US), Eyeshields, Gloves



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Christine C Conwell et al.
Biochemistry, 43(18), 5380-5387 (2004-05-05)
Millimolar concentrations of divalent cations are shown to affect the size of toroids formed when DNA is condensed by multivalent cations. The origins of this effect were explored by varying the order in which MgCl(2) was added to a series
Yee Siew Choong et al.
Journal of molecular graphics & modelling, 29(6), 834-842 (2011-03-05)
The high typhoid incidence rate in developing and under-developed countries emphasizes the need for a rapid, affordable and accessible diagnostic test for effective therapy and disease management. TYPHIDOT®, a rapid dot enzyme immunoassay test for typhoid, was developed from the
T Allers et al.
Nucleic acids research, 28(2), e6-e6 (1999-12-22)
The Holliday junction is a central intermediate in genetic recombination. This four-stranded DNA structure is capable of spontaneous branch migration, and is lost during standard DNA extraction protocols. In order to isolate and characterize recombination intermediates that contain Holliday junctions



Global Trade Item Number

SKUGTIN
H7891-25G04061833076569
H7891-10G04061833076552
H7891-5G04061833804858