Skip to Content
Merck
CN

Key Documents

View All Documentation

H8017

Hydroxocobalamin acetate

vitamin B12 analog

Synonym(s):

Vitamin B12a acetate

Sign In to View Organizational & Contract Pricing.

Select a Size

Change View

About This Item

Empirical Formula (Hill Notation):
C64H91CoN13O16P
CAS Number:
22465-48-1
Molecular Weight:
1388.39
PubChem Substance ID:
329815248
eCl@ss:
34058004
UNSPSC Code:
12352205
NACRES:
NA.79
EC Number:
245-019-7
MDL number:
MFCD00082532
Technical Service
Need help? Our team of experienced scientists is here for you.
Let Us Assist

biological source

synthetic (organic)

Quality Level

200

assay

≥95% (HPLC)

form

powder

technique(s)

HPLC: suitable

color

red to brown

storage temp.

2-8°C

SMILES string

CC(CNC(=O)CC[C@]1(C)[C@@H](CC(N)=O)[C@H]2N=C1C(C)=C3N=C(C=C4N=C(C(C)=C5[C@@H](CCC(N)=O)[C@](C)(CC(N)=O)[C@@]2(C)N5[Co]OC(C)=O)[C@@](C)(CC(N)=O)[C@@H]4CCC(N)=O)C(C)(C)[C@@H]3CCC(N)=O)OP([O-])(=O)O[C@H]6[C@@H](O)[C@H](O[C@@H]6CO)n7cnc8cc(C)c(C)cc78

InChI

1S/C62H90N13O14P.C2H4O2.Co/c1-29-20-39-40(21-30(29)2)75(28-70-39)57-52(84)53(41(27-76)87-57)89-90(85,86)88-31(3)26-69-49(83)18-19-59(8)37(22-46(66)80)56-62(11)61(10,25-48(68)82)36(14-17-45(65)79)51(74-62)33(5)55-60(9,24-47(67)81)34(12-15-43(63)77)38(71-55)23-42-58(6,7)35(13-16-44(64)78)50(72-42)32(4)54(59)73-56;1-2(3)4;/h20-21,23,28,31,34-37,41,52-53,56-57,76,84H,12-19,22,24-27H2,1-11H3,(H15,63,64,65,66,67,68,69,71,72,73,74,77,78,79,80,81,82,83,85,86);1H3,(H,3,4);/q;;+2/p-3/t31?,34-,35-,36-,37+,41-,52-,53-,56-,57+,59-,60+,61+,62+;;/m1../s1

InChI key

QHSPIHUMLGFPKX-WYVZQNDMSA-K

General description

Hydroxocobalamin is an analog of vitamin B12 with OH as an alkyl group. Vitamin B12 cobalamin refers to a group of chemically-related cobalt containing molecules.

Biochem/physiol Actions

Vitamin B12 cobalamin is involved in DNA synthesis and fatty acid synthesis. It also plays a vital role as a coenzyme in the conversion of mitochondrial methylmalonyl co-enzyme A to succinyl co-enzyme A. Vitamin B12 cobalamin is also involved in neurotransmitter synthesis and erythropoiesis. It also functions in the synthesis and maintenance of myelin sheath. Hydroxocobalamin (vitamin B12a, OHCbl) and cyanocobalamin (CNCbl) are storage and delivery forms.

Still not finding the right product?

Explore all of our products under Hydroxocobalamin acetate

pictograms

Health hazard
GHS08

signalword

Warning

hcodes

H351

Hazard Classifications

Carc. 2

Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

Choose from one of the most recent versions:

Certificates of Analysis (COA)

Lot/Batch Number
SLCL9766
SLCD6763
SLBT4289
SLBK9993V
SLBC1324

Don't see the Right Version?

If you require a particular version, you can look up a specific certificate by the Lot or Batch number.

Search for a COA

Already Own This Product?

Find documentation for the products that you have recently purchased in the Document Library.

Visit the Document Library

Articles

Vitamin B12, Cobalamin, in Cell Culture

Importance and uses of Vitamin B12 in serum-free eukaryotic, including hybridoma and Chinese Hamster Ovary (CHO) cell cultures

Hydroxocobalamin association during cell culture results in pink therapeutic proteins
MAbs, 5(6), 974-981 (2013)
Photodegradation of cobalamins in aqueous solutions and in human blood
Juzeniene A and Nizauskaite Z
Journal of Photochemistry and Photobiology. B, Biology, 122(21), 7-14 (2013)
Iron, vitamin B12 and folate
Moll R and Davis B
Medicine, 45(4), 198-203 (2017)
View All Related Papers

Global Trade Item Number

SKUGTIN
H8017-1G04061826691335
H8017-250MG04061833804988