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Merck
CN

HMI1002

MISSION® microRNA Mimic

hsa-miR-122

Synonym(s):

hsa-miR-122-5p

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About This Item

UNSPSC Code:
12352200
NACRES:
NA.51
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product line

MISSION®

form

solid

mature sequence

UGGAGUGUGACAAUGGUGUUUG

Sanger mature/minor accession no.

Sanger microRNA accession no.

storage temp.

−20°C

Gene Information

General description

The ready-to-use MISSION miRNA mimics are small, double-stranded RNA molecules designed to mimic endogenous mature miRNA molecules when introduced into cells. miRNA are known to regulate gene expression in a variety of manners, including translational repression, mRNA cleavage and deadenylation. MISSION miRNA Mimics, a member of MISSION RNAi product family, provides miRNA researchers with a range of options from individual MISSION mimics to a full library of human miRNA mimics based on latest version of miRBase (currently hosted by the University of Manchester, previously hosted by the Sanger Institute).

  • Optimized and ready for transfection.
  • Novel MISSION miRNA mimic design has been functionally tested for knockdown efficiency against natural miRNA targets.
  • Unique MISSION miRNA mimic design significantly reduces possible sense strand off target effects.
  • Available as a whole human library and individual miRNA targets.

Other Notes

miRBase V18 Mature ID update: hsa-miR-122-5p

Legal Information

MISSION is a registered trademark of Merck KGaA, Darmstadt, Germany


Storage Class

13 - Non Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

Regulatory Information

常规特殊物品

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Virginie Vignard et al.
Cancer immunology research, 8(2), 255-267 (2019-12-21)
MicroRNAs (miRNA), small noncoding RNAs that regulate gene expression, exist not only in cells but also in a variety of body fluids. These circulating miRNAs could enable intercellular communication. miRNAs are packaged in membrane-encapsulated vesicles, such as exosomes, or protected



Global Trade Item Number

SKUGTIN
HMI1002-5NMOL04061831384666