Key Documents

View All Documentation

I110

Ibuprofen

Name: Ibuprofen
Brand: SIGMA

Synonym(s):

α-Methyl-4-(isobutyl)phenylacetic acid, (±)-2-(4-Isobutylphenyl)propanoic acid

Select a Size

Change View

About This Item

Empirical Formula (Hill Notation):

C₁₃H₁₈O₂

CAS Number:

15687-27-1

Molecular Weight:

206.28

NACRES:

NA.24

PubChem Substance ID:

329815343

UNSPSC Code:

41116107

EC Number:

239-784-6

MDL number:

MFCD00010393

Technical Service

Need help? Our team of experienced scientists is here for you.

Let Us Assist

Properties

assay

≥98% (HPLC)

Quality Level

100

technique(s)

HPLC: suitable, gas chromatography (GC): suitable

color

white to off-white

application(s)

forensics and toxicology
pharmaceutical (small molecule)

format

neat

SMILES string

CC(C)Cc1ccc(cc1)C(C)C(O)=O

InChI

1S/C13H18O2/c1-9(2)8-11-4-6-12(7-5-11)10(3)13(14)15/h4-7,9-10H,8H2,1-3H3,(H,14,15)

InChI key

HEFNNWSXXWATRW-UHFFFAOYSA-N

Gene Information

human ... PTGS1(5742), PTGS2(5743)

Description

General description

Ibuprofen is a non-steroidal and anti-inflammatory drug, which finds a variety of therapeutic applications in relieving pain and inflammatory disorders.

Application

Ibuprofen has been used as a test compound in studying its removal from aqueous solutions via adsorption on titanium dioxide based multi-walled carbon nanotube membranes. It is also used as an external reference standard in order to validate the purity of the macro-cyclic peptides, an emerging therapeutic drug modality, using nuclear magnetic resonance technique (NMR).

Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

Biochem/physiol Actions

Cyclooxygenase (COX) inhibitor that has greater activity against COX-1 than against COX-2.

Other Notes

Find a digital Reference Material for this product available on our online platform ChemisTwin® for NMR. You can use this digital equivalent on ChemisTwin® for your sample identity confirmation and compound quantification (with digital external standard). An NMR spectrum of this substance can be viewed and an online comparison against your sample can be performed with a few mouseclicks. Learn more here and start your free trial.

Still not finding the right product?

Explore all of our products under Ibuprofen

pictograms

GHS07

signalword

Warning

hcodes

H302,H319,H335

pcodes

P261 - P264 - P271 - P280 - P301 + P312 - P305 + P351 + P338

Hazard Classifications

Acute Tox. 4 Oral - Eye Irrit. 2 - STOT SE 3

target_organs

Respiratory system

Storage Class

11 - Combustible Solids

wgk

WGK 1

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

dust mask type N95 (US), Eyeshields, Gloves

Choose from one of the most recent versions:

Certificates of Analysis (COA)

Lot/Batch Number

Don't see the Right Version?

If you require a particular version, you can look up a specific certificate by the Lot or Batch number.

Search for a COA

Already Own This Product?

Find documentation for the products that you have recently purchased in the Document Library.

Visit the Document Library

Comparison of an antiinflammatory dose of ibuprofen, an analgesic dose of ibuprofen, and acetaminophen in the treatment of patients with osteoarthritis of the knee.

Bradley D J, et al.

The New England Journal of Medicine, 325(2), 87-91 (1991)

Tiered analytics for purity assessment of macrocyclic peptides in drug discovery: Analytical consideration and method development

Cutrone QJ, et al.

Journal of Pharmaceutical and Biomedical Analysis, 138, 166-174 (2017)

Cell Surface Extensions: Advances in Research and Application: 2011 Edition (2012)

View All Related Papers

Global Trade Item Number

SKU	GTIN
I110-1G	04061833847466
I110-5G	04061833847473