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About This Item
Form:
lyophilized powder
Assay:
≥90% (PAGE)
Biological source:
bovine milk
biological source
bovine milk
Quality Level
assay
≥90% (PAGE)
form
lyophilized powder
UniProt accession no.
storage temp.
2-8°C
Gene Information
bovine ... LGB(280838)
General description
A member of the lipocalin family, β-Lactoglobulin (βLg) is a small protein of 162 amino acids with a molecular mass of ∼18,400 Da. It features an eight-stranded β-barrel (strands A-H) succeeded by a three-turn a-helix and a final β-strand (strand I) that forms part of the dimerization interface.
Milk from dairy cows contains the protein β-lactoglobulin (BLG). It naturally occurs in a number of genetic variants, and the most prevalent bovine variants are BLG A and BLG B.
Application
β-Lactoglobulin from bovine milk was used to test the allergen-responsive CD4+ CD25+ regulatory T cells in children who have outgrown cow′s milk allergy. It is also used to test the competitive displacement of β-lactoglobulin by Tween 20 from oil-water and air-water interfaces.
Preparation Note
Crystallized
Analysis Note
May not contain folate binding protein; not recommended for folate analysis.
Other Notes
Contains β-lactoglobulins A and B which can be isolated chromatographically.
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Storage Class
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type N95 (US)
Regulatory Information
低风险生物材料
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Janire Orcajo et al.
Analytica chimica acta, 1052, 163-169 (2019-01-28)
Immunochemical detection of food allergens is usually based on the use of polyclonal or monoclonal immunoglobulins G (IgG) antibodies. However, due to differences in epitopes recognition between IgG and IgE, an epitope modification during food processing can potentially alter allergenicity
The Competitive Displacement of ?-Lactoglobulin by Tween 20 from Oil-Water and Air-Water Interfaces
Peter J. Wilde, David C. Clark
Journal of Colloid and Interface Science, 155, 48-54 (1993)
Unni Haddeland et al.
Pediatric allergy and immunology : official publication of the European Society of Pediatric Allergy and Immunology, 16(2), 104-112 (2005-03-25)
The hygiene hypothesis implies that the increasing prevalence of allergy in 'westernized' countries is explained by reduced bacterial exposure in early life, but the underlying mechanism remains elusive. We therefore wanted to study the effect of bacterial lipopolysaccharide (LPS) on
Global Trade Item Number
| SKU | GTIN |
|---|---|
| L0130-1G | 04061833945575 |
| L0130-5G | 04061833945582 |