L4754
3-sn-Lysophosphatidylethanolamine from egg yolk
Type I, ≥99%
Synonym(s):
1-Acyl-sn-glycero-3-phospho(2-aminoethanol), L-α-Lysocephalin, L-α-Lysophosphatidylethanolamine
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About This Item
biological source
egg yolk
Quality Level
type
Type I
assay
≥99%
form
powder
lipid type
phosphoglycerides
shipped in
ambient
storage temp.
−20°C
General description
Lysophosphatidylethanolamine (LysoPE), a prominent part of lysophospholipid, is obtained by the partial hydrolysis of phosphatidylethanolamine.
Application
3-sn-Lysophosphatidylethanolamine from egg yolk has been used:
- to prepare liposomes for liposome binding and vesiculation assay
- as a phospholipid standard in high-performance thin layer chromatography (HPTLC) to detect the phospholipid composition of platelet-derived microparticles
- as a phospholipid standard in thin layer chromatography (TLC) to identify phospholipid in parasitophorous vacuoles (PV) containing Leishmania amazonensis
Biochem/physiol Actions
L-α-Lysophosphatidylethanolamines from egg yolk are enriched with stearate and palmitate acylated fatty acids.
Lysophosphatidylethanolamine (LPE) participates in the physiological and pathological processes of the nervous system. It plays a key role in the function of the cell membrane, apoptosis, oxidative stress, and inflammatory responses.
Analysis Note
Contains primarily stearic and palmitic acids.
Storage Class
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type N95 (US)
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Yuan-Yuan Zhao et al.
Journal of chromatography. A, 1218(32), 5470-5479 (2011-07-09)
A hydrophilic interaction liquid chromatography-tandem mass spectrometry (HILIC LC-MS/MS) method using multiple scan modes was developed to separate and quantify 11 compounds and lipid classes including acetylcholine (AcCho), betaine (Bet), choline (Cho), glycerophosphocholine (GPC), lysophosphatidylcholine (LPC), lysophosphatidylethanolamine (LPE), phosphatidylcholine (PC)
Nguyen Dang Hung et al.
Lipids, 46(10), 893-906 (2011-07-12)
In the present study, the anti-inflammatory action of lysophosphatidylethanolamine (lysoPtdEtn), orally administered, in zymosan A-induced peritonitis was examined. Oral administration of 2-DHA-lysoPtdEtn (ED(50), ~111 μg/kg) or 2-ARA-lysoPtdEtn (ED(50), 221 μg/kg) was found to inhibit the plasma leakage in mice treated with zymosan
Madhavi Avadhani et al.
Journal of bacteriology, 188(24), 8543-8550 (2006-10-10)
Short-chain alcohol dehydrogenases (SCADHs) synthesize a variety of intercellular signals and other chemically diverse products. It is difficult to predict the substrate of a SCADH on the basis of amino acid sequence homology, as the substrates are not known for
Global Trade Item Number
| SKU | GTIN |
|---|---|
| L4754-5MG | 04061833957707 |
| L4754-100MG | 04061833957684 |
| L4754-25MG | 04061833957691 |