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Merck
CN

M1778

Mucin from porcine stomach

Type III, bound sialic acid 0.5-1.5 %, partially purified powder

Synonym(s):

MUC

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About This Item

CAS Number:
UNSPSC Code:
12352202
EC Number:
282-010-7
NACRES:
NA.61
MDL number:
Form:
partially purified powder
Biological source:
Porcine stomach
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biological source

Porcine stomach

Quality Level

type

Type III

form

partially purified powder

composition

bound sialic acid, 0.5-1.5%

technique(s)

microbiological culture: suitable

solubility

NaOH: soluble 20 mg/mL

storage temp.

2-8°C

General description

Mucins or mucus glycoproteins are the main macromolecular components of mammalian mucus. It was also used in a study to evaluate the sputum smears concentrated by cyto-centrifugation for detection of acid-fast bacilli.

Application

Mucin from porcine stomach was used in studies on the binding site of the galactose-specific agglutinin PA-IL from Pseudomonas aeruginosa.

Biochem/physiol Actions

Mucus forms the protective cover for all epithelial surfaces. The major structural component of mucus is gel-forming mucins. The mucus layer covering the intestinal epithelium has the MUC2 mucin as its central molecule. MUC2 is produced by goblet cells.

Preparation Note

Prepared according to the method of Glenister, et al., for use in complex growth media for dental plaque bacteria.


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Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

Regulatory Information

低风险生物材料

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Articles

Understand sialic acid structure, function, signaling, and modifications. Easily find products for sialic acid research.


Anastasia Matthies et al.
Applied and environmental microbiology, 74(15), 4847-4852 (2008-06-10)
The metabolism of isoflavones by gut bacteria plays a key role in the availability and bioactivation of these compounds in the intestine. Daidzein and genistein are the most common dietary soy isoflavones. While daidzein conversion yielding equol has been known
Helen Rose et al.
The Journal of antimicrobial chemotherapy, 63(3), 502-510 (2009-01-21)
The Burkholderia cepacia complex (Bcc) species are important opportunistic pathogens with intrinsic antibiotic resistance. They are also well known as contaminants of disinfectants, yet their biocide susceptibility has not been studied in detail. We investigated Bcc biocide susceptibility and correlated
Kenny C Mok et al.
mBio, 11(6) (2020-12-10)
The beneficial human gut bacterium Akkermansia muciniphila provides metabolites to other members of the gut microbiota by breaking down host mucin, but most of its other metabolic functions have not been investigated. A. muciniphila strain MucT is known to use



Global Trade Item Number

SKUGTIN
M1778-100G04061834041108
M1778-10G04061835557660