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M6145

1-Thioglycerol

liquid, BioReagent, suitable for cell culture, ≥97% (titration)

Synonym(s):

α-Monothioglycerol, α-Thioglycerol, 3-Mercapto-1,2-propanediol

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About This Item

Linear Formula:
HSCH2CH(OH)CH2OH
CAS Number:
96-27-5
Molecular Weight:
108.16
UNSPSC Code:
12352211
NACRES:
NA.75
PubChem Substance ID:
24897080
EC Number:
202-495-0
Beilstein/REAXYS Number:
1732046
MDL number:
MFCD00004879
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biological source

synthetic (organic)

Quality Level

200

product line

BioReagent

assay

≥97% (titration)

form

liquid

technique(s)

cell culture | mammalian: suitable, single cell analysis: suitable

refractive index

n20/D 1.527 (lit.)

bp

118 °C/5 mmHg (lit.)

solubility

water: miscible 0.1 M

density

1.25 g/mL at 25 °C (lit.)

storage temp.

2-8°C

SMILES string

OCC(O)CS

InChI

1S/C3H8O2S/c4-1-3(5)2-6/h3-6H,1-2H2

InChI key

PJUIMOJAAPLTRJ-UHFFFAOYSA-N

Application

Cell culture studies of embryonic cortical and hippocampal neurons, mouse bone marrow mast cell lines, and human Β cell lines have utilized 1-thioglycerol as a component of the culture medium to stimulate proliferation.

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pictograms

Skull and crossbones
GHS06

signalword

Danger

Hazard Classifications

Acute Tox. 3 Dermal - Acute Tox. 3 Inhalation - Acute Tox. 4 Oral - Skin Irrit. 2 - Skin Sens. 1B

Storage Class

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

wgk

WGK 3

flash_point_f

210.2 °F - closed cup

flash_point_c

99 °C - closed cup

ppe

Eyeshields, Faceshields, Gloves, type ABEK (EN14387) respirator filter

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Certificates of Analysis (COA)

Lot/Batch Number
MKCQ0094
MKCP3167
MKCN8746
MKCN4649
MKCM6335

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Philip E Boulais et al.
Immunity, 49(4), 627-639 (2018-10-14)
The non-hematopoietic cell fraction of the bone marrow (BM) is classically identified as CD45- Ter119- CD31- (herein referred to as triple-negative cells or TNCs). Although TNCs are believed to contain heterogeneous stromal cell populations, they remain poorly defined. Here we
Suji Lee et al.
Stem cells (Dayton, Ohio), 36(10), 1552-1566 (2018-07-14)
Although autologous induced pluripotent stem cells (iPSCs) can potentially be useful for treating patients without immune rejection, in reality it will be extremely expensive and labor-intensive to make iPSCs to realize personalized medicine. An alternative approach is to make use
Yankun Yu et al.
Assay and drug development technologies, 16(4), 222-229 (2018-05-31)
Co-administration of sofosbuvir, an anti-hepatitis C virus medication, and antiarrhythmic amiodarone causes symptomatic severe bradycardia in patients and animal models. However, in a few in vitro studies, the combination of sofosbuvir and amiodarone resulted in tachycardiac effects in human induced
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Global Trade Item Number

SKUGTIN
M6145-100ML04061834060666
M6145-250ML04061834060673
M6145-25ML04061834060680