IgG1, Kappa from murine myeloma

Immunoglobulins (Igs) belongs to the immunoglobulin super-family. IgG is the abundant immunoglobulin in human serum. The four classes of IgG can be IgG1, IgG2, IgG3 and IgG4.

Mammalian immunoglobins contain either lambda or kappa light chains.

IgG1, Kappa from murine myeloma has been used in:

• chromatin immunoprecipitation (ChIP)
• immunofluorescence
• immunocapture
• enzyme immunoassay
• immunohistochemistry

IgG1 is the most abundant and its deficiency results in hypogammaglobulinemia. IgG antibody have enormous therapeutic potential and the Fc region is involved the development of therapeutic antibody.

Specificity is determined by mouse monoclonal isotyping strips. The purified immunoglobulin preparation is non-reactive with mouse IgA, IgM, IgG2a, IgG2b, or IgG3.

Solution in 0.02 M Tris buffered saline, pH 8.0, containing 0.02% sodium azide

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