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M9130

4-Methylumbelliferyl-β-D-glucuronide hydrate

≥98% (HPLC), BioReagent, for identification of transformed plants

Synonym(s):

4-Methylumbelliferyl-β-D-glucopyranosiduronic acid, MUG

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About This Item

Empirical Formula (Hill Notation):
C16H16O9 · xH2O
CAS Number:
881005-91-0
Molecular Weight:
352.29 (anhydrous basis)
NACRES:
NA.52
PubChem Substance ID:
329818083
UNSPSC Code:
12352200
MDL number:
MFCD09039280
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grade

Molecular Biology

Quality Level

200

product line

BioReagent

assay

≥98% (HPLC)

form

powder

solubility

pyridine: 50 mg/mL, clear, colorless to very faintly yellow

storage temp.

−20°C

SMILES string

O.CC1=CC(=O)Oc2cc(O[C@@H]3O[C@@H]([C@@H](O)[C@H](O)[C@H]3O)C(O)=O)ccc12

InChI

1S/C16H16O9.H2O/c1-6-4-10(17)24-9-5-7(2-3-8(6)9)23-16-13(20)11(18)12(19)14(25-16)15(21)22;/h2-5,11-14,16,18-20H,1H3,(H,21,22);1H2/t11-,12-,13+,14-,16+;/m0./s1

InChI key

URVSQZMOFUEQAW-YYHOVTOASA-N

General description

MUG is a chemical commonly used for the detection of transformed plants. MUG shows low levels of fluorescence until treatment with glucuronidase (GUS) encoded in transformed plants. Transformed plants can be identified by their MUG fluorescence.

Application

Suitable for fluorescent detection of glucuronidase gene expression in plants.

Preparation Note

Product is soluble in molecular biology grade water at a concentration of 0.35 mg/ml.

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Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

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Certificates of Analysis (COA)

Lot/Batch Number
SLCK7876
SLCG6223
SLBV8189
SLCC4849
SLBP6765V

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Articles

Probiotics and Human Health

Probiotics exhibit an inhibitory effect on pathogens, help prevent chronic intestinal inflammatory diseases or atopic syndromes, and support the immune system.

L J Moberg
Applied and environmental microbiology, 50(6), 1383-1387 (1985-12-01)
An assay procedure to screen for Escherichia coli in foods by using 4-methylumbelliferyl-beta-D-glucuronide (MUG) incorporated into lauryl tryptose (LST) broth was evaluated. The beta-glucuronidase produced by E. coli cleaves the MUG substrate to yield a fluorescent end product. E. coli-negative
Andrew G Kunihiro et al.
Molecular nutrition & food research, 64(14), e2000072-e2000072 (2020-06-09)
Curcumin prevents bone loss in resorptive bone diseases and inhibits osteoclast formation, a key process driving bone loss. Curcumin circulates as an inactive glucuronide that can be deconjugated in situ by bone's high β-glucuronidase (GUSB) content, forming the active aglycone.
M C Thaller et al.
Journal of clinical microbiology, 26(4), 791-793 (1988-04-01)
A new selective, differential plating medium to screen the common gram-negative urinary tract pathogens is described. The medium combines adonitol fermentation, phenylalanine deaminase, and beta-glucuronidase tests and allows the indole and cytochrome oxidase tests to be performed directly from the
View All Related Papers

Global Trade Item Number

SKUGTIN
M9130-1G04061835516643
M9130-100MG04061835574360
M9130-250MG04061834063933
M9130-25MG04061834063940