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Merck
CN

MAK108

PLTP Activity Assay Kit

Supplied by Roar Biomedical, Inc.

Synonym(s):

Phospholipid transfer protein activity assay kit

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About This Item

NACRES:
NA.84
UNSPSC Code:
12161503
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usage

sufficient for 100 fluorometric tests

application(s)

pharmaceutical

detection method

fluorometric

relevant disease(s)

cardiovascular diseases

storage temp.

2-8°C

Gene Information

human ... PLTP(5360)

General description

Phospholipid transfer protein (PLTP) is a protein present in normal human plasma. PLTP transfers phospholipids among lipoproteins in plasma.

Application

Suitable to determine Phospholipid transfer protein (PLTP) activity in plasma or serum (fresh or frozen) as well as other sources of PLTP.

Biochem/physiol Actions

The PLTP Activity Assay Kit includes proprietary substrates to detect PLTP mediated transfer of fluorescent substrate. Transfer activity results in increased fluorescent emission intensity (λEx = 465 nm/λEm = 535 nm) from the assay.


Storage Class

10 - Combustible liquids

wgk

WGK 1

Regulatory Information

低风险生物材料

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Alexina Orsoni et al.
Journal of lipid research, 53(4), 767-775 (2012-02-18)
In familial hypercholesterolemia (FH), low HDL cholesterol (HDL-C) levels are associated with functional alterations of HDL particles that reduce their capacity to mediate the reverse cholesterol transport (RCT) pathway. The objective of this study was to evaluate the consequences of
Natacha Bellanger et al.
Arteriosclerosis, thrombosis, and vascular biology, 31(7), 1675-1681 (2011-04-30)
Low high-density lipoprotein (HDL) cholesterol levels are frequently observed in familial hypercholesterolemia (FH) and might be associated with functional alterations of HDL particles that may influence their efficaciousness in the reverse cholesterol transport pathway. We evaluated key steps of the
Sander J Robins et al.
Atherosclerosis, 228(1), 230-236 (2013-03-13)
Cholesteryl ester transfer protein (CETP) and phospholipid transfer protein (PLTP) are two genetically-related plasma proteins involved in the exchange of cholesteryl esters and phospholipids between high-density lipoproteins (HDL) and other lipoproteins. Although low CETP and high PLTP activity both result



Global Trade Item Number

SKUGTIN
MAK108-1KT04061834065333