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Merck
CN

N1627

4-Nitrophenyl β-D-glucuronide

≥98% (TLC)

Synonym(s):

4-Nitrophenyl β-D-glucuronide, 4-Nitrophenyl-β-D-glucopyranosiduronic acid, PNPG

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About This Item

Empirical Formula (Hill Notation):
C12H13NO9
CAS Number:
Molecular Weight:
315.23
UNSPSC Code:
12352200
NACRES:
NA.52
PubChem Substance ID:
EC Number:
233-753-0
Beilstein/REAXYS Number:
1438576
MDL number:
Technical Service
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grade

Molecular Biology

Quality Level

assay

≥98% (TLC)

form

powder

solubility

H2O: soluble 100 mg/mL, clear

storage temp.

−20°C

SMILES string

O[C@@H]1[C@@H](O)[C@@H](O[C@@H]([C@H]1O)C(O)=O)Oc2ccc(cc2)[N+]([O-])=O

InChI

1S/C12H13NO9/c14-7-8(15)10(11(17)18)22-12(9(7)16)21-6-3-1-5(2-4-6)13(19)20/h1-4,7-10,12,14-16H,(H,17,18)/t7-,8-,9+,10-,12+/m0/s1

InChI key

QSUILVWOWLUOEU-GOVZDWNOSA-N

General description

Chromogenic substrate for β-glucuronidase (GUS) gene detection.

Application

4-Nitrophenyl β-D-glucuronide has been used as substrate in acetate buffer to measure β-glucuronidase.


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Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)



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Articles

Drug conjugate analysis and the enzymatic hydrolysis of glucuronides

Probiotics exhibit an inhibitory effect on pathogens, help prevent chronic intestinal inflammatory diseases or atopic syndromes, and support the immune system.


C F Franssen et al.
Journal of the American Society of Nephrology : JASN, 10(7), 1506-1515 (1999-07-15)
Previously, it was found that patients with necrotizing crescentic glomerulonephritis (NCGN) and anti-neutrophil cytoplasmic autoantibodies (ANCA) directed against proteinase 3 (anti-PR3) had a faster deterioration of renal function and more active renal vasculitic lesions than patients with ANCA directed against
Analysis of Fluorescent Compounds in Urine by Liquid Chromatography
T. Hanaia & J. Huberta
Journal of Liquid Chromatography, 7, 1627-1642 (1984)
H Iwabuchi et al.
Journal of chromatography, 414(1), 139-148 (1987-02-20)
Molecular-secondary-ion mass spectrometry (SIMS) is a suitable method for the analysis of nonvolatile substances such as conjugated metabolites of drugs. We have developed a simple method for the direct SIMS measurement of conjugates following thin-layer chromatography without any extraction procedure.



Global Trade Item Number

SKUGTIN
N1627-2G04061833077191
N1627-100MG04061833077160
N1627-1G04061826695036
N1627-250MG04061834109570
N1627-25MG04061834109587
N1627-50MG04061834109594