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N3139

β-Nicotinamide adenine dinucleotide phosphate sodium salt hydrate

powder, BioReagent, suitable for cell culture

Synonym(s):

Triphosphopyridine nucleotide sodium salt hydrate

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About This Item

Empirical Formula (Hill Notation):
C21H27N7NaO17P3 · xH2O
CAS Number:
698999-85-8
Molecular Weight:
765.39 (anhydrous basis)
NACRES:
NA.75
PubChem Substance ID:
24897624
UNSPSC Code:
12352205
MDL number:
MFCD00150480
Form:
powder
Assay:
≥98% (HPLC), ≥98% (spectrophotometric assay)
Solubility:
H2O: 50 mg/mL
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product line

BioReagent

Quality Level

200

assay

≥98% (HPLC), ≥98% (spectrophotometric assay)

form

powder

technique(s)

cell culture | mammalian: suitable

mp

175-178 °C (dec.) (lit.)

solubility

H2O: 50 mg/mL

storage temp.

−20°C

SMILES string

O[C@H]1[C@@H](O)[C@H]([N+]2=CC(C(N)=O)=CC=C2)O[C@@H]1COP(OP(OC[C@H]3O[C@@H](N(C=N4)C5=C4C(N)=NC=N5)[C@H](OP(O)(O)=O)[C@@H]3O)([O-])=O)([O-])=O.O.[Na+]

InChI

1S/C21H28N7O17P3.Na.H2O/c22-17-12-19(25-7-24-17)28(8-26-12)21-16(44-46(33,34)35)14(30)11(43-21)6-41-48(38,39)45-47(36,37)40-5-10-13(29)15(31)20(42-10)27-3-1-2-9(4-27)18(23)32;;/h1-4,7-8,10-11,13-16,20-21,29-31H,5-6H2,(H7-,22,23,24,25,32,33,34,35,36,37,38,39);;1H2/q;+1;/p-1/t10-,11-,13-,14-,15-,16-,20-,21-;;/m1../s1

InChI key

CYQLUFJYVTUUFN-WUEGHLCSSA-M

Application

β-Nicotinamide adenine dinucleotide phosphate sodium salt hydrate has been used in the purification and crystallization of CHORD–Sgt1 cytochrome b 5 reductases (CS–b5R). It has also been used as a supplement in Dulbecco′s modified Eagle′s medium (DMEM)/F-12 medium for direct hepatic reprogramming using mouse embryonic fibroblasts (MEFs).

Biochem/physiol Actions

Electron acceptor
Nicotinamide adenine dinucleotide phosphate (NADP) is an indispensable cofactor that participates in cellular redox reactions. It acts as a hydride-accepting coenzyme and participates in substrate oxidation reactions during metabolism.

Packaging

Packaged by solid weight.

Analysis Note

Meets or exceeds NRC specifications and is comparable to any commercial preparation available.

Other Notes

This is the common form of NADP. Do not confuse with 3′−NADP or α-NADP.

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pictograms

Exclamation mark
GHS07

signalword

Warning

hcodes

H319

Hazard Classifications

Eye Irrit. 2

Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

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Certificates of Analysis (COA)

Lot/Batch Number
SLCH2227
SLCD2419
SLBZ6728
SLBV0167
SLBQ2888V

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Global Trade Item Number

SKUGTIN
N3139-1G04061834115823
N3139-100MG04061834115816
N3139-250MG04061834115830