N3877
Potassium 4-nitrophenyl sulfate
sulfatase substrate, chromogenic, ≥98% (TLC), powder
Synonym(s):
4-Nitrophenyl sulfate potassium salt
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About This Item
Linear Formula:
NO2C6H4OSO2OK
CAS Number:
Molecular Weight:
257.26
NACRES:
NA.32
PubChem Substance ID:
UNSPSC Code:
12352204
EC Number:
228-288-5
MDL number:
Beilstein/REAXYS Number:
3786392
Product Name
Potassium 4-nitrophenyl sulfate, sulfatase substrate
Quality Level
assay
≥98% (TLC)
form
powder
mp
246-250 °C (lit.)
solubility
water: 50 mg/mL, clear, colorless to very faintly greenish-yellow (to Very Light Yellow)
shipped in
wet ice
storage temp.
−20°C
SMILES string
[K+].[O-][N+](=O)c1ccc(OS([O-])(=O)=O)cc1
InChI
1S/C6H5NO6S.K/c8-7(9)5-1-3-6(4-2-5)13-14(10,11)12;/h1-4H,(H,10,11,12);/q;+1/p-1
InChI key
BITVAZYUWRLLCN-UHFFFAOYSA-M
General description
Chromogenic sulfatase substrate.
Application
Potassium 4-nitrophenyl sulfate has been used:
- as a substrate to measure arylsulfatase activity in cell-free coelomic fluid
- as a substrate for p-nitrophenyl glycoside-based enzyme assay
- to inhibit arylsulfatase
- as an inorganic analog of organic aryl ester sulphate
Storage Class
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type N95 (US)
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A dietary fiber-deprived gut microbiota degrades the colonic mucus barrier and enhances pathogen susceptibility
Desai MS, et al.
Cell, 167(5), 1339-1353 (2016)
E S Lin et al.
Biochemical and biophysical research communications, 271(3), 818-822 (2000-05-18)
The sulfation of a nucleotide is an indispensable step for the sulfuryl group transfer in a biological system. The product and cosubstrate of sulfotransferase in physiological condition are adenosine 3',5'-bisphosphate (PAP) and 3'-phospho adenosine 5'-phosphosulfate (PAPS), respectively. We find that
Maternal and neonatal urinary excretion of sulfate and glucuronide ritodrine conjugates
Brashear WT, et al.
Clinical Pharmacology and Therapeutics, 44(6), 634-641 (1988)
Global Trade Item Number
| SKU | GTIN |
|---|---|
| N3877-500MG | 04061834116325 |
| N3877-1G | 04061835506477 |
| N3877-5G | 04061835506484 |