N7627
L-Norvaline
≥99% (TLC)
Synonym(s):
(S)-(+)-2-Aminopentanoic acid, (S)-2-Aminovaleric acid
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About This Item
Linear Formula:
CH3CH2CH2CH(NH2)CO2H
CAS Number:
Molecular Weight:
117.15
NACRES:
NA.26
PubChem Substance ID:
eCl@ss:
32160406
UNSPSC Code:
12352209
EC Number:
229-543-3
MDL number:
Beilstein/REAXYS Number:
1721162
Product Name
L-Norvaline, arginase inhibitor
Quality Level
assay
≥99% (TLC)
form
powder
color
white
mp
>300 °C (lit.)
application(s)
detection
SMILES string
CCC[C@H](N)C(O)=O
InChI
1S/C5H11NO2/c1-2-3-4(6)5(7)8/h4H,2-3,6H2,1H3,(H,7,8)/t4-/m0/s1
InChI key
SNDPXSYFESPGGJ-BYPYZUCNSA-N
Application
- Nanodrugs mediate TAMs-related arginine metabolism interference to boost photodynamic immunotherapy.: This study explores the use of nanodrugs to interfere with arginine metabolism in tumor-associated macrophages (TAMs), enhancing the efficacy of photodynamic immunotherapy. L-Norvaline plays a crucial role in this metabolic interference (Chen et al., 2024).
Biochem/physiol Actions
L-Norvaline enhances NO production from activated macrophages.
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Storage Class
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type N95 (US)
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Ying-Chen Lin et al.
The New phytologist, 223(4), 1904-1917 (2019-05-16)
Choline kinase catalyzes the initial reaction step of choline metabolism that produces phosphocholine, a prerequisite for the biosynthesis of a primary phospholipid phosphatidylcholine. However, the primary choline kinase and its role in plant growth remained elusive in seed plants. Here
C I Chang et al.
The American journal of physiology, 274(1 Pt 2), H342-H348 (1998-02-12)
In macrophages and many other cell types, L-arginine is used as a substrate by both nitric oxide synthase (NOS) and arginase to produce nitric oxide (NO) and urea, respectively. Because the availability of L-arginine is a major determinant for NO
Seyed Abdollah Hosseini et al.
International journal of molecular sciences, 20(4) (2019-03-01)
The importance of magnesium (Mg) for plant growth is well-documented. Silicon (Si)-mediated alleviation of mineral deficiencies has been also reported in a number of plant species; however, there is no report on the relevance of Si nutrition in plants grown
Global Trade Item Number
| SKU | GTIN |
|---|---|
| N7627-5G | 04061834118107 |
| N7627-10G | 04061834118084 |
| N7627-1G | 04061834118091 |