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O6754

1-Oleoyl-2-acetyl-sn-glycerol

≥97% (TLC), oil

Synonym(s):

(9Z)-9-Octadecenoic acid (2S)-2-(acetyloxy)-3-hydroxypropyl ester, 1-(cis-9-Octadecenoyl)-2-acetyl-sn-glycerol, 2-Acetyl-1-oleoyl-sn-glycerol, DG(18:1(9Z)/2:0/0:0), OAG

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About This Item

Empirical Formula (Hill Notation):
C23H42O5
CAS Number:
86390-77-4
Molecular Weight:
398.58
UNSPSC Code:
12352211
NACRES:
NA.25
PubChem Substance ID:
24898039
MDL number:
MFCD00166985
Beilstein/REAXYS Number:
8168731
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biological source

synthetic (organic)

Quality Level

200

assay

≥97% (TLC)

form

oil

solubility

ethanol: 20 mg/mL (lit.)(lit.), DMSO: soluble (lit.)(lit.)

functional group

ketone

lipid type

neutral glycerides

shipped in

dry ice

storage temp.

−20°C

SMILES string

CCCCCCCC\C=C/CCCCCCCC(=O)OC[C@H](CO)OC(C)=O

InChI

1S/C23H42O5/c1-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-18-23(26)27-20-22(19-24)28-21(2)25/h10-11,22,24H,3-9,12-20H2,1-2H3/b11-10-/t22-/m0/s1

InChI key

PWTCCMJTPHCGMS-YRBAHSOBSA-N

Gene Information

human ... PRKCA(5578)

Biochem/physiol Actions

1-Oleoyl-2-acetyl-sn-glycerol is a synthetic, cell permeable diacylglycerol analog. It is often used as an activator of calcium-dependent protein kinase C (PKC).

Disclaimer

Some isomerization may occur during storage or in solution.

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Storage Class

10 - Combustible liquids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

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Certificates of Analysis (COA)

Lot/Batch Number
SLCC2381
SLBX2612
SLBR9038V
SLBL7693V
SLBH2763V

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Kathryn P Burdon et al.
American journal of ophthalmology, 159(1), 31-36 (2014-09-23)
To determine if open-angle glaucoma (OAG)-associated single nucleotide polymorphisms (SNPs) are associated with incident glaucoma and if such genetic information is useful in OAG risk prediction. Case-control from within a population-based longitudinal study. study population: Individuals aged over 49 years
Saifur Rahman et al.
Scientific reports, 7(1), 12881-12881 (2017-10-19)
The store-operated calcium entry (SOCE) pathway is an important route for generating cytosolic Ca
Christian Feisst et al.
Cellular and molecular life sciences : CMLS, 66(16), 2759-2771 (2009-07-07)
We previously showed that, in vitro, hyperforin from St. John's wort (Hypericum perforatum) inhibits 5-lipoxygenase (5-LO), the key enzyme in leukotriene biosynthesis. Here, we demonstrate that hyperforin possesses a novel and unique molecular pharmacological profile as a 5-LO inhibitor with
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Global Trade Item Number

SKUGTIN
O6754-10MG04061832950402
O6754-25MG04061832950426
O6754-5MG04061832950433