P0381
Pyrogallol
≥98% (HPLC)
Synonym(s):
1,2,3-Trihydroxybenzene, 2,3-Dihydroxyphenol, Pyrogallic acid
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About This Item
Linear Formula:
C6H3(OH)3
CAS Number:
Molecular Weight:
126.11
UNSPSC Code:
12191503
NACRES:
NA.21
PubChem Substance ID:
EC Number:
201-762-9
Beilstein/REAXYS Number:
907431
MDL number:
Assay:
≥98% (HPLC)
Grade:
HPLC grade
Technique(s):
HPLC: suitable
Bp:
309 °C (lit.)
Vapor pressure:
10 mmHg ( 167.7 °C)
grade
HPLC grade
Quality Level
vapor density
4.4 (vs air)
vapor pressure
10 mmHg ( 167.7 °C)
assay
≥98% (HPLC)
form
powder
technique(s)
HPLC: suitable
pH
5.8 (10 g/L)
bp
309 °C (lit.)
mp
133-134 °C (lit.)
solubility
ethanol: 50 mg/mL, clear, colorless
application(s)
cell analysis
SMILES string
Oc1cccc(O)c1O
InChI
1S/C6H6O3/c7-4-2-1-3-5(8)6(4)9/h1-3,7-9H
InChI key
WQGWDDDVZFFDIG-UHFFFAOYSA-N
General description
Pyrogallol is a polyphenol and allelochemical, found on Microcystis aeruginosa and Emblica officinalis.
Application
Pyrogallol has been used:
- in the superoxide dismutase (SOD) assay
- to induce modification in mitochondrial DNA and to characterize the same
- as a standard to confirm the presence of pyrogallol in butanol fraction of white rose petal extract
Biochem/physiol Actions
Pyrogallol induces superoxide anion (O2-) generation and in the presence of metal ions, it stimulates oxidative damage to DNA and lipids.
Analysis Note
May contain black specks.
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signalword
Warning
Hazard Classifications
Acute Tox. 4 Dermal - Acute Tox. 4 Inhalation - Acute Tox. 4 Oral - Aquatic Chronic 3 - Muta. 2
Storage Class
11 - Combustible Solids
wgk
WGK 2
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
dust mask type N95 (US), Eyeshields, Faceshields, Gloves
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Neuroprotective effects of a butanol fraction of Rosa hybrida petals in a middle cerebral artery occlusion model
Yang G, et al.
Biomolecules & Therapeutics, 21(6), 454-454 (2013)
Caspase inhibitor decreases apoptosis in pyrogallol-treated lung cancer Calu-6 cells via the prevention of GSH depletion
Han YH, et al.
International Journal of Oncology, 33(5), 1099-1105 (2008)
Pyrogallol induces G2-M arrest in human lung cancer cells and inhibits tumor growth in an animal model
Yang CJ, et al.
Lung Cancer, 66(2), 162-168 (2009)
Global Trade Item Number
| SKU | GTIN |
|---|---|
| P0381-250G | 04061834291152 |
| P0381-25G | 04061834291169 |
| P0381-100G | 04061835326976 |
| P0381-500G | 04061835326983 |