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P0503

O-Phosphorylethanolamine

Name: <I>O</I>-Phosphorylethanolamine
Brand: SIGMA

Synonym(s):

2-Aminoethyl dihydrogen phosphate, O-Phosphocolamine, O-Phosphoethanolamine, Colaminephosphoric acid

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About This Item

Linear Formula:

NH₂CH₂CH₂OPO₃H₂

CAS Number:

1071-23-4

Molecular Weight:

141.06

UNSPSC Code:

12161700

NACRES:

NA.25

PubChem Substance ID:

24898109

EC Number:

213-988-5

Beilstein/REAXYS Number:

1758916

MDL number:

MFCD00008178

Form:

powder

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Properties

form

powder

storage temp.

−20°C

SMILES string

NCCOP(O)(O)=O

InChI

1S/C2H8NO4P/c3-1-2-7-8(4,5)6/h1-3H2,(H2,4,5,6)

InChI key

SUHOOTKUPISOBE-UHFFFAOYSA-N

Description

Application

O-Phosphorylethanolamine has been used:

in LHC-8 medium as a supplement in culturing the transformed human liver epithelial (THLE)-2 and THLE-3 cells
in C-reactive protein (CRP) binding sucrose flotation experiment
to incubate phosphomonoesters with anion-exchange chromatography (AEC) fractions for the detection of phosphatase activity
to add in the washed beads for the preparation of phosphorylethanolamine (Pet) -conjugated sepharose column for chromatographic purification of mutant CRP

Biochem/physiol Actions

Phosphorylethanolamine participates in phospholipid metabolism. Its release can be stimulated occasionally by depolarizing stimuli. Reduction of phosphorylethanolamine levels has been observed in Alzheimer′s and Huntington′s disease.

Packaging

Bottomless glass bottle. Contents are inside inserted fused cone.

Storage Class

11 - Combustible Solids

wgk

WGK 3

ppe

Eyeshields, Faceshields, Gloves, type P3 (EN 143) respirator cartridges

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Phosphoethanolamine-complexed C-reactive protein: a pharmacological-like macromolecule that binds to native low-density lipoprotein in human serum

Singh SK, et al.

Clinica Chimica Acta; International Journal of Clinical Chemistry, 394(1-2), 94-98 (2008)

The phosphocholine-binding pocket on C-reactive protein is necessary for initial protection of mice against pneumococcal infection

Gang TB, et al.

Test, jbc-M112 (2012)

Novel Phospholipase A activity secreted byLegionella species

Flieger A, et al.

Journal of Bacteriology, 182(5), 1321-1327 (2000)

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Global Trade Item Number

SKU	GTIN
P0503-100G	04061834304104
P0503-10MG	04061833255483
P0503-5G	04061834304135
P0503-1G	04061834304111
P0503-25G	04061833612507
P0503-500G	04061834304128