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P2658

Poly-L-lysine hydrochloride

Name: Poly-<SC>L</SC>-lysine hydrochloride
Brand: SIGMA

suitable for cell culture, Mol wt 15,000-30,000

Synonym(s):

L-Lysine hydrochloride homopolymer

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About This Item

CAS Number:

26124-78-7

UNSPSC Code:

12352209

eCl@ss:

32160406

NACRES:

NA.26

MDL number:

MFCD00081870

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Properties

Product Name

Poly-L-lysine hydrochloride, mol wt 15,000-30,000

form

powder or solid

Quality Level

200

mol wt

15,000-30,000

technique(s)

cell culture | mammalian: suitable

color

white to light yellow

application(s)

cell analysis

storage temp.

−20°C

Description

Application

Poly-L-lysine hydrochloride has been used to coat glass slides and coverslips to facilitate cell attachment.

Poly-lysine with mol. wt. >70,000 is useful in promoting cell adhesion to solid substrates.

Biochem/physiol Actions

L-Lysine is believed to prevent osteoporosis of bones, which is a characteristics of vascular calcification. Glutaric aciduria type I and pyridoxine-dependent epilepsy occurs due to lack of L-lysine catabolic pathway. Lysine participates in the regulation of NO (nitric oxide) synthesis. It possesses antiviral activity, therefore it is used in the treatment of Herpes simplex. L-Lysine is associated with a number of biochemical reactions such as acetylation, O-linked glycosylation, ubiquitination and protein methylation. Poly-L-lysine is considered as a biocompatible polymer and serves for the purpose of drug delivery across cell membrane. It is useful as one of the nanosized contrast agents in MRI (magnetic resonance imaging).

Analysis Note

Molecular weight based on viscosity.

Other Notes

For additional technical information on polyamino acids please visit the Polyamino acid FAQ resource.

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Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

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Articles

Layer-by-Layer (LbL) Assembly, A "Gentle Yet Flexible" Method Toward Functional Biomaterials

Recently, layer-by-layer (LbL) assembly has emerged as a versatile, gentle and, simple method for immobilization of functional molecules in an easily controllable thin film morphology.1,2 In this short review, we introduce recent advances in functional systems fabricated by using the mild, yet adaptable LbL technique.

Poly(Amino Acid) Block Copolymers for Drug Delivery and other Biomedical Applications

Humankind has utilized protein materials throughout its existence, starting with the use of materials such as wool and silk for warmth and protection from the elements and continuing with the use of recombinant DNA techniques to synthesize proteins with unique and useful properties.

Global Trade Item Number

SKU	GTIN
P2658-500MG	04061832779461
P2658-100MG	04061835547470
P2658-1G	04061826757567
P2658-25MG	04061834365136