Key Documents

View All Documentation

P5084

PTIO

Name: PTIO
Brand: SIGMA

NO activity inhibitor, powder

Synonym(s):

2-Phenyl-4,4,5,5-tetramethylimidazoline-1-oxyl 3-oxide

Select a Size

Change View

About This Item

Empirical Formula (Hill Notation):

C₁₃H₁₇N₂O₂

CAS Number:

18390-00-6

Molecular Weight:

233.29

UNSPSC Code:

12352200

PubChem Substance ID:

329820215

NACRES:

NA.32

MDL number:

MFCD00059929

Technical Service

Need help? Our team of experienced scientists is here for you.

Let Us Assist

Properties

Product Name

PTIO,

Quality Level

200

form

powder

storage temp.

2-8°C

SMILES string

CC1(C)N([O])C(c2ccccc2)=[N+]([O-])C1(C)C

InChI

1S/C13H17N2O2/c1-12(2)13(3,4)15(17)11(14(12)16)10-8-6-5-7-9-10/h5-9H,1-4H3

InChI key

DYUUGILMVYJEHY-UHFFFAOYSA-N

Description

Application

2-phenyl-4, 4, 5, 5,-tetramethylimidazoline-1-oxyl 3-oxide (PTIO) has been used as a nitric oxide (NO) scavenger.

Biochem/physiol Actions

2-phenyl-4, 4, 5, 5,-tetramethylimidazoline-1-oxyl 3-oxide (PTIOs) derivatives react with nitric oxide (NO) to yield the corresponding imino nitroxides (PTIs) and nitrogen dioxide (NO2).

A stable radical scavenger for nitric oxide; affects NO without affecting NO synthase; has significant inhibitory activity against NO biological actions.

Stable radical scavenger for nitric oxide without affecting NO synthase; inhibits NO activity.

Still not finding the right product?

Explore all of our products under PTIO

Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

dust mask type N95 (US), Eyeshields, Gloves

Choose from one of the most recent versions:

Certificates of Analysis (COA)

Lot/Batch Number

Don't see the Right Version?

If you require a particular version, you can look up a specific certificate by the Lot or Batch number.

Search for a COA

Already Own This Product?

Find documentation for the products that you have recently purchased in the Document Library.

Visit the Document Library

In vivo target sites of nitric oxide in photosynthetic electron transport as studied by chlorophyll fluorescence in pea leaves.

Barnabás Wodala et al.

Plant physiology, 146(4), 1920-1927 (2008-02-05)

The role of nitric oxide (NO) in photosynthesis is poorly understood as indicated by a number of studies in this field with often conflicting results. As various NO donors may be the primary source of discrepancies, the aim of this

A protein synthesis and nitric oxide-dependent presynaptic enhancement in persistent forms of long-term potentiation.

Victoria P A Johnstone et al.

Learning & memory (Cold Spring Harbor, N.Y.), 18(10), 625-633 (2011-09-22)

Long-term potentiation (LTP) is an important process underlying learning and memory in the brain. At CA3-CA1 synapses in the hippocampus, three discrete forms of LTP (LTP1, 2, and 3) can be differentiated on the basis of maintenance and induction mechanisms.

NMDA receptor activation enhances inhibitory GABAergic transmission onto hippocampal pyramidal neurons via presynaptic and postsynaptic mechanisms.

Jiu-Gang Xue et al.

Journal of neurophysiology, 105(6), 2897-2906 (2011-04-08)

N-methyl-D-aspartate (NMDA) receptors (NMDARs) are implicated in synaptic plasticity and modulation of glutamatergic excitatory transmission. Effect of NMDAR activation on inhibitory GABAergic transmission remains largely unknown. Here, we report that a brief application of NMDA could induce two distinct actions

View All Related Papers

Global Trade Item Number

SKU	GTIN
P5084-100MG	04061834375807
P5084-25MG	04061834375821