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P5155

D-Pantothenic acid hemicalcium salt

Name: <SC>D</SC>-Pantothenic acid hemicalcium salt
Brand: SIGMA

BioReagent, suitable for cell culture, suitable for insect cell culture, suitable for plant cell culture

Synonym(s):

(R)-(+)-N-(2,4-Dihydroxy-3,3-dimethyl-1-oxobutyl)-β-alanine hemicalcium salt, Calcium D-pantothenate, Vitamin B₅

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About This Item

Linear Formula:

HOCH₂C(CH₃)₂CH(OH)CONHCH₂CH₂CO₂ ·1/2Ca

CAS Number:

137-08-6

Molecular Weight:

238.27

NACRES:

NA.75

PubChem Substance ID:

24898601

eCl@ss:

34058012

UNSPSC Code:

12352205

EC Number:

205-278-9

MDL number:

MFCD00002766

Beilstein/REAXYS Number:

3769272

Assay:

≥98% (TLC)

Form:

powder

Quality level:

200

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Properties

biological source

synthetic (organic)

Quality Level

200

product line

BioReagent

assay

≥98% (TLC)

form

powder

mol wt

M_w 238.27 g/mol

technique(s)

cell culture | insect: suitable, cell culture | mammalian: suitable, cell culture | plant: suitable

color

white to off-white

pH

7.0-8 (25 °C, 50 g/L)

solubility

water: soluble 50 mg/mL, clear, colorless

storage temp.

2-8°C

SMILES string

CC(C)(CO)[C@@H](O)C(=O)NCCC(=O)O[Ca]OC(=O)CCNC(=O)[C@H](O)C(C)(C)CO

InChI

1S/2C9H17NO5.Ca/c2*1-9(2,5-11)7(14)8(15)10-4-3-6(12)13;/h2*7,11,14H,3-5H2,1-2H3,(H,10,15)(H,12,13);/q;;+2/p-2/t2*7-;/m00./s1

InChI key

FAPWYRCQGJNNSJ-UBKPKTQASA-L

Description

General description

Plants and microorganisms, such as Escherichia coli are the major sources of D-pantothenic acid. It is water soluble and quite stable to heating.

Due to the unstable, hygroscopic nature of the free acid, the calcium salt is employed.

Application

D-Pantothenic acid hemicalcium salt has been used:

as a component of FMX-turbodoma- derived media
as a supplement in DMEM (Dulbecco′s modified eagle media)/F-12 used for cell proliferation
as a supplement in preadipocyte media

Precursor in the biosynthesis of coenzyme A.

Biochem/physiol Actions

Along with coenzyme A (CoA, D-pantothenic acid is a precursor for acyl carrier protein. These are essential cofactors involved in fat, protein and carbohydrate metabolism. It also participates in the formation of acetylcholine neurotransmitter. D-pantothenic acid is considered as a source of nutrition and possesses immune function by mediating antibody formation. The production of cortisone is supported by D-pantothenic acid. It is essential for adrenal gland activity.

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Storage Class

11 - Combustible Solids

wgk

WGK 1

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

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3T3-L1 cells and perivascular adipocytes are not equivalent in amine transporter expression

Ismail A, et al.

Febs Letters, 591(1), 137-144 (2017)

Stopping the Clock, 184-184 (2003)

Organisation of the pantothenate (vitamin B5) biosynthesis pathway in higher plants

Ottenhof HH, et al.

The Plant Journal, 37(1), 61-72 (2004)

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Global Trade Item Number

SKU	GTIN
P5155-500G	04061834376316
P5155-100G	04061834376309