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Merck
CN

P5295

Piracetam

Synonym(s):

2-(2-Oxopyrrolidino)acetamide, 2-Oxo-1-pyrrolidineacetamide

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About This Item

Empirical Formula (Hill Notation):
C6H10N2O2
CAS Number:
Molecular Weight:
142.16
NACRES:
NA.77
PubChem Substance ID:
UNSPSC Code:
41116107
EC Number:
231-312-7
MDL number:
Form:
powder
Quality level:
Technical Service
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form

powder

Quality Level

SMILES string

NC(=O)CN1CCCC1=O

InChI

1S/C6H10N2O2/c7-5(9)4-8-3-1-2-6(8)10/h1-4H2,(H2,7,9)

InChI key

GMZVRMREEHBGGF-UHFFFAOYSA-N

Gene Information

Application

Piracetam has been used to study crystal structure and physicochemical properties of six co-crystals of piracetam. It has also been used to study its in vitro antioxidant properties.

Biochem/physiol Actions

Piracetam (2-oxo-1-pyrrolidinyl-acetamide) is a nootropic drug, which enhances memory and facilitates learning. Piracetam also acts as a vasodilator and improves blood flow. It has a potential to treat cognitive impairment in aging, brain injury, memory and balance problems. In addition, piracetam is also used to treat peripheral vascular disease.


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Storage Class

11 - Combustible Solids

wgk

WGK 2

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)



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Piracetam and vinpocetine ameliorate rotenone-induced Parkinsonism in rats
Zaitone SA, et al.
International Journal of Pharmaceutics, 44(6), 774-774 (2012)
Hélène Amieva et al.
PloS one, 8(1), e52755-e52755 (2013-01-18)
Numerous studies have looked at the potential benefits of various nootropic drugs such as Ginkgo biloba extract (EGb761®; Tanakan®) and piracetam (Nootropyl®) on age-related cognitive decline often leading to inconclusive results due to small sample sizes or insufficient follow-up duration.
Rute A P Costa et al.
European journal of pharmacology, 701(1-3), 82-86 (2013-01-22)
Mitochondrial oxidative stress followed by membrane permeability transition (MPT) has been considered as a possible mechanism for statins cytotoxicity. Statins use has been associated with reduced risk of cancer incidence, especially prostate cancer. Here we investigated the pathways leading to



Global Trade Item Number

SKUGTIN
P5295-25G04061834378709